信号通路: Focal adhesion;ECM-receptor interaction;Pathways in cancer;Small cell lung cancer;
功能: domain:Domain G is globular and is part of the major cell-binding site located in the long arm of the laminin heterotrimer.,function:Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.,similarity:Contains 1 laminin IV type A domain.,similarity:Contains 1 laminin N-terminal domain.,similarity:Contains 22 laminin EGF-like domains.,similarity:Contains 5 laminin G-like domains.,subcellular location:Major component.,subunit:Laminin-15 complex is an heterotrimer composed of three chains (alpha-5/beta-2/gamma-3) which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end.,tissue specificity:Expressed in heart, lung, kidney, skeletal muscle, pancreas, retina and placenta. Little or no expression in brain and liver.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Secreted, extracellular space, extracellular matrix, basement membrane. Major component.
组织表达: Expressed in heart, lung, kidney, skeletal muscle, pancreas, retina and placenta. Little or no expression in brain and liver.
信号通路: Focal adhesion;ECM-receptor interaction;Pathways in cancer;Small cell lung cancer;
功能: domain:Domain G is globular and is part of the major cell-binding site located in the long arm of the laminin heterotrimer.,function:Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.,similarity:Contains 1 laminin IV type A domain.,similarity:Contains 1 laminin N-terminal domain.,similarity:Contains 22 laminin EGF-like domains.,similarity:Contains 5 laminin G-like domains.,subcellular location:Major component.,subunit:Laminin-15 complex is an heterotrimer composed of three chains (alpha-5/beta-2/gamma-3) which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end.,tissue specificity:Expressed in heart, lung, kidney, skeletal muscle, pancreas, retina and placenta. Little or no expression in brain and liver.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Secreted, extracellular space, extracellular matrix, basement membrane. Major component.
组织表达: Expressed in heart, lung, kidney, skeletal muscle, pancreas, retina and placenta. Little or no expression in brain and liver.