其他名称： KCNT1; KIAA1422; Potassium channel subfamily T member 1; KCa4.1
实测条带： 140kD
功能： function:Outwardly rectifying potassium channel subunit that may co-assemble with other Slo-type channel subunits. Activated by high intracellular sodium or chloride levels. Activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. May be regulated by calcium in the absence of sodium ions (in vitro).,PTM:Phosphorylated by protein kinase C. Phosphorylation of the C-terminal domain increases channel activity.,similarity:Belongs to the potassium channel family. Calcium-activated subfamily.,similarity:Contains 1 RCK N-terminal domain.,subunit:Interacts with CRBN via its cytoplasmic C-terminus.,tissue specificity:Highest expression in liver, brain and spinal cord. Lowest expression in skeletal muscle.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane ; Multi-pass membrane protein .
组织表达： Highest expression in liver, brain and spinal cord. Lowest expression in skeletal muscle.
其他名称： KCNT1; KIAA1422; Potassium channel subfamily T member 1; KCa4.1
实测条带： 140kD
功能： function:Outwardly rectifying potassium channel subunit that may co-assemble with other Slo-type channel subunits. Activated by high intracellular sodium or chloride levels. Activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. May be regulated by calcium in the absence of sodium ions (in vitro).,PTM:Phosphorylated by protein kinase C. Phosphorylation of the C-terminal domain increases channel activity.,similarity:Belongs to the potassium channel family. Calcium-activated subfamily.,similarity:Contains 1 RCK N-terminal domain.,subunit:Interacts with CRBN via its cytoplasmic C-terminus.,tissue specificity:Highest expression in liver, brain and spinal cord. Lowest expression in skeletal muscle.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane ; Multi-pass membrane protein .
组织表达： Highest expression in liver, brain and spinal cord. Lowest expression in skeletal muscle.
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