Intestinal Cell Kinase Polyclonal Antibody

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商品货号： PLA016488

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： ICK
蛋白名称： Serine/threonine-protein kinase ICK
Human_gene_id： 22858
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22858
Human_swiss_prot_no： Q9UPZ9
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9UPZ9/entry
Mouse_gene_id： 56542
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56542
Mouse_swiss_prot_no： Q9JKV2
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9JKV2
Rat_gene_id： 84411
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=84411
Rat_swiss_prot_no： Q62726
Rat_swiss_link： http://www.uniprot.org/uniprot/Q62726
特异性： Intestinal Cell Kinase Polyclonal Antibody detects endogenous levels of Intestinal Cell Kinase protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： ICK; KIAA0936; Serine/threonine-protein kinase ICK; Intestinal cell kinase; hICK; Laryngeal cancer kinase 2; LCK2; MAK-related kinase; MRK
实测条带： 65kD
功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,disease:Defects in ICK are the cause of endocrine-cerebroosteodysplasia (ECO) [MIM:612651]. ECO is a previously unidentified neonatal lethal recessive disorder with multiple anomalies involving the endocrine, cerebral, and skeletal systems.,function:May play a key role in the development of multiple organ systems and particularly in cardiac development.,PTM:Autophosphorylated on serine and threonine residues. May play a role in enzyme activation.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.,similarity:Contains 1 protein kinase domain.,subcellular location:Nuclear localization has been observed with a GFP-tagged construct in transfected HeLa cells (PubMed:12103360). Cytosolic localization was shown in rat embryonic cardiomyocytes by immunostaining (PubMed:8570168).,tissue specificity:Expressed in heart, brain, placenta, pancreas, thymus, prostate, testis, ovary, small intestine and colon, with highest levels in placenta and testis. Not detected in spleen. Also expressed in many cancer cell lines.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm, cytosol . Cell projection, cilium . Cytoplasm, cytoskeleton, cilium basal body . Also found at the ciliary tip (PubMed:24797473). Nuclear localization has been observed with a GFP-tagged construct in transfected HeLa cells (PubMed:12103360, PubMed:19185282). .; [Isoform 2]: Cytoplasm . Predominant cytoplasmic localization has been observed with a N-terminally GFP-tagged construct. .
组织表达： Expressed in heart, brain, placenta, pancreas, thymus, prostate, testis, ovary, small intestine and colon, with highest levels in placenta and testis. Not detected in spleen. Also expressed in many cancer cell lines.
科研货号： PLA016488

Intestinal Cell Kinase Polyclonal Antibody

Catalog No PLA016488

Product information

基因名称： ICK
蛋白名称： Serine/threonine-protein kinase ICK
Human_gene_id： 22858
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22858
Human_swiss_prot_no： Q9UPZ9
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9UPZ9/entry
Mouse_gene_id： 56542
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56542
Mouse_swiss_prot_no： Q9JKV2
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9JKV2
Rat_gene_id： 84411
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=84411
Rat_swiss_prot_no： Q62726
Rat_swiss_link： http://www.uniprot.org/uniprot/Q62726
特异性： Intestinal Cell Kinase Polyclonal Antibody detects endogenous levels of Intestinal Cell Kinase protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： ICK; KIAA0936; Serine/threonine-protein kinase ICK; Intestinal cell kinase; hICK; Laryngeal cancer kinase 2; LCK2; MAK-related kinase; MRK
实测条带： 65kD
功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,disease:Defects in ICK are the cause of endocrine-cerebroosteodysplasia (ECO) [MIM:612651]. ECO is a previously unidentified neonatal lethal recessive disorder with multiple anomalies involving the endocrine, cerebral, and skeletal systems.,function:May play a key role in the development of multiple organ systems and particularly in cardiac development.,PTM:Autophosphorylated on serine and threonine residues. May play a role in enzyme activation.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.,similarity:Contains 1 protein kinase domain.,subcellular location:Nuclear localization has been observed with a GFP-tagged construct in transfected HeLa cells (PubMed:12103360). Cytosolic localization was shown in rat embryonic cardiomyocytes by immunostaining (PubMed:8570168).,tissue specificity:Expressed in heart, brain, placenta, pancreas, thymus, prostate, testis, ovary, small intestine and colon, with highest levels in placenta and testis. Not detected in spleen. Also expressed in many cancer cell lines.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm, cytosol . Cell projection, cilium . Cytoplasm, cytoskeleton, cilium basal body . Also found at the ciliary tip (PubMed:24797473). Nuclear localization has been observed with a GFP-tagged construct in transfected HeLa cells (PubMed:12103360, PubMed:19185282). .; [Isoform 2]: Cytoplasm . Predominant cytoplasmic localization has been observed with a N-terminally GFP-tagged construct. .
组织表达： Expressed in heart, brain, placenta, pancreas, thymus, prostate, testis, ovary, small intestine and colon, with highest levels in placenta and testis. Not detected in spleen. Also expressed in many cancer cell lines.
科研货号： PLA016488

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