InsP 3-kinase C Polyclonal Antibody

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商品货号： PLA016475

适应性： 人,大鼠,小鼠,

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： ITPKC
蛋白名称： Inositol-trisphosphate 3-kinase C
Human_gene_id： 80271
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=80271
Human_swiss_prot_no： Q96DU7
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q96DU7/entry
Mouse_swiss_prot_no： Q7TS72
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q7TS72
特异性： InsP 3-kinase C Polyclonal Antibody detects endogenous levels of InsP 3-kinase C protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： ITPKC; IP3KC; Inositol-trisphosphate 3-kinase C; Inositol 1; 4,5-trisphosphate 3-kinase C; IP3 3-kinase C; IP3K C; InsP 3-kinase C
实测条带： 102kD
功能： catalytic activity:ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate.,disease:Genetic variations in ITPKC influence susceptibility to Kawasaki disease [MIM:611775]; also known as mucocutaneous lymph node syndrome or infantile polyarteritis. Kawasaki disease is an acute, self-limited vasculitis of infants and children characterized by prolonged fever unresponsive to antibiotics, polymorphous skin rash, erythema of the oral mucosa, lips, and tongue, erythema of the palms and soles, bilateral conjunctival injection, and cervical lymphadenopathy. Coronary artery aneurysms develop in 15 to 25% of those left untreated, making Kawasaki disease the leading cause of acquired heart disease among children in developed countries.,enzyme regulation:Activated by calcium/calmodulin. Inhibited by high concentrations of the substrate Ins(1,2,4)P3, and allosterically activated by the product Ins(1,3,4,5)P4.,function:Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate.,similarity:Belongs to the inositol phosphokinase (IPK) family.,subcellular location:Shuttles actively between nucleus and cytoplasm with both nuclear import and nuclear export activity.,tissue specificity:Highly expressed in pancreas, skeletal muscle, liver, placenta and weakly in kidney and brain.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm . Shuttles actively between nucleus and cytoplasm with both nuclear import and nuclear export activity. .
组织表达： Highly expressed in pancreas, skeletal muscle, liver, placenta and weakly in kidney and brain.
科研货号： PLA016475

InsP 3-kinase C Polyclonal Antibody

Catalog No PLA016475

Product information

基因名称： ITPKC
蛋白名称： Inositol-trisphosphate 3-kinase C
Human_gene_id： 80271
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=80271
Human_swiss_prot_no： Q96DU7
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q96DU7/entry
Mouse_swiss_prot_no： Q7TS72
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q7TS72
特异性： InsP 3-kinase C Polyclonal Antibody detects endogenous levels of InsP 3-kinase C protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： ITPKC; IP3KC; Inositol-trisphosphate 3-kinase C; Inositol 1; 4,5-trisphosphate 3-kinase C; IP3 3-kinase C; IP3K C; InsP 3-kinase C
实测条带： 102kD
功能： catalytic activity:ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate.,disease:Genetic variations in ITPKC influence susceptibility to Kawasaki disease [MIM:611775]; also known as mucocutaneous lymph node syndrome or infantile polyarteritis. Kawasaki disease is an acute, self-limited vasculitis of infants and children characterized by prolonged fever unresponsive to antibiotics, polymorphous skin rash, erythema of the oral mucosa, lips, and tongue, erythema of the palms and soles, bilateral conjunctival injection, and cervical lymphadenopathy. Coronary artery aneurysms develop in 15 to 25% of those left untreated, making Kawasaki disease the leading cause of acquired heart disease among children in developed countries.,enzyme regulation:Activated by calcium/calmodulin. Inhibited by high concentrations of the substrate Ins(1,2,4)P3, and allosterically activated by the product Ins(1,3,4,5)P4.,function:Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate.,similarity:Belongs to the inositol phosphokinase (IPK) family.,subcellular location:Shuttles actively between nucleus and cytoplasm with both nuclear import and nuclear export activity.,tissue specificity:Highly expressed in pancreas, skeletal muscle, liver, placenta and weakly in kidney and brain.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm . Shuttles actively between nucleus and cytoplasm with both nuclear import and nuclear export activity. .
组织表达： Highly expressed in pancreas, skeletal muscle, liver, placenta and weakly in kidney and brain.
科研货号： PLA016475

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