其他名称: IL4I1; FIG1; L-amino-acid oxidase; LAAO; LAO; Interleukin-4-induced protein 1; IL4-induced protein 1; Protein Fig-1; hFIG1
实测条带: 60kD
信号通路: Alanine; aspartate and glutamate metabolism;Cysteine and methionine metabolism;Valine; leucine and isoleucine degradation;Tyrosine metabolism;Phenylalanine metabolism;Tryptophan metabolism;Phenylalanine; tyrosine and tryptophan biosynthesis;
功能: catalytic activity:An L-amino acid + H(2)O + O(2) = a 2-oxo acid + NH(3) + H(2)O(2).,cofactor:FAD.,function:Lysosomal L-amino-acid oxidase with highest specific activity with phenylalanine. May play a role in lysosomal antigen processing and presentation.,induction:By interleukin-4.,similarity:Belongs to the flavin monoamine oxidase family. FIG1 subfamily.,tissue specificity:Primarily found in immune tissues (isoform 1).,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Secreted . Lysosome . Cytoplasmic vesicle, secretory vesicle, acrosome . Secreted at the immunological synapse. .
组织表达: Primarily found in immune tissues, with the highest expression in lymph nodes and spleen (PubMed:12031486, PubMed:12446450). Present in germinal center macrophages and inflammatory myeloid cells and antigen-presenting cells (at protein level) (PubMed:17356132). Also present in spermatozoa (at protein level) (PubMed:25767141). Highly expressed in primary mediastinal large B-cell lymphoma, a specific subtype of diffuse large B-cell lymphoma (PubMed:12446450). Expressed by neoplastic cells of several B-cell lymphomas and by tumor-associated macrophages (PubMed:19436310).
其他名称: IL4I1; FIG1; L-amino-acid oxidase; LAAO; LAO; Interleukin-4-induced protein 1; IL4-induced protein 1; Protein Fig-1; hFIG1
实测条带: 60kD
信号通路: Alanine; aspartate and glutamate metabolism;Cysteine and methionine metabolism;Valine; leucine and isoleucine degradation;Tyrosine metabolism;Phenylalanine metabolism;Tryptophan metabolism;Phenylalanine; tyrosine and tryptophan biosynthesis;
功能: catalytic activity:An L-amino acid + H(2)O + O(2) = a 2-oxo acid + NH(3) + H(2)O(2).,cofactor:FAD.,function:Lysosomal L-amino-acid oxidase with highest specific activity with phenylalanine. May play a role in lysosomal antigen processing and presentation.,induction:By interleukin-4.,similarity:Belongs to the flavin monoamine oxidase family. FIG1 subfamily.,tissue specificity:Primarily found in immune tissues (isoform 1).,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Secreted . Lysosome . Cytoplasmic vesicle, secretory vesicle, acrosome . Secreted at the immunological synapse. .
组织表达: Primarily found in immune tissues, with the highest expression in lymph nodes and spleen (PubMed:12031486, PubMed:12446450). Present in germinal center macrophages and inflammatory myeloid cells and antigen-presenting cells (at protein level) (PubMed:17356132). Also present in spermatozoa (at protein level) (PubMed:25767141). Highly expressed in primary mediastinal large B-cell lymphoma, a specific subtype of diffuse large B-cell lymphoma (PubMed:12446450). Expressed by neoplastic cells of several B-cell lymphomas and by tumor-associated macrophages (PubMed:19436310).