其他名称： IGFBP3; IBP3; Insulin-like growth factor-binding protein 3; IBP-3; IGF-binding protein 3; IGFBP-3
实测条带： 31kD
信号通路： p53;
功能： developmental stage:IGFBP3 levels are higher during extrauterine life and peak during puberty.,domain:The thyroglobulin type-1 domain mediates interaction with HN.,function:IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.,induction:IGFBP3 levels increase in the presence of IGF1, insulin and other growth-stimulating factors such as growth hormone, epidermal growth factor, and phorbol esters.,online information:The Singapore human mutation and polymorphism database,similarity:Contains 1 IGFBP N-terminal domain.,similarity:Contains 1 thyroglobulin type-1 domain.,subunit:Interacts with XLKD1 (By similarity). Binds IGF2 more than IGF1. Forms a ternary complex of about 140 to 150 kDa with IGF1 or IGF2 and a 85 kDa glycoprotein (ALS). Interacts with HN.,tissue specificity:Expressed by most tissues.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Secreted .
组织表达： Expressed by most tissues. Present in plasma.
科研货号： PLA016427
IGFBP3 Polyclonal Antibody
Catalog NoPLA016427
Product information
基因名称： IGFBP3
蛋白名称： Insulin-like growth factor-binding protein 3
其他名称： IGFBP3; IBP3; Insulin-like growth factor-binding protein 3; IBP-3; IGF-binding protein 3; IGFBP-3
实测条带： 31kD
信号通路： p53;
功能： developmental stage:IGFBP3 levels are higher during extrauterine life and peak during puberty.,domain:The thyroglobulin type-1 domain mediates interaction with HN.,function:IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.,induction:IGFBP3 levels increase in the presence of IGF1, insulin and other growth-stimulating factors such as growth hormone, epidermal growth factor, and phorbol esters.,online information:The Singapore human mutation and polymorphism database,similarity:Contains 1 IGFBP N-terminal domain.,similarity:Contains 1 thyroglobulin type-1 domain.,subunit:Interacts with XLKD1 (By similarity). Binds IGF2 more than IGF1. Forms a ternary complex of about 140 to 150 kDa with IGF1 or IGF2 and a 85 kDa glycoprotein (ALS). Interacts with HN.,tissue specificity:Expressed by most tissues.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Secreted .
组织表达： Expressed by most tissues. Present in plasma.
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