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HSL Polyclonal Antibody
商品货号: PLA016391
适 应 性: 人,小鼠,大鼠
WB IHC IF ELISA
¥600元
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MSDS
说明书
商品描述
  • 基因名称: LIPE
  • 蛋白名称: Hormone-sensitive lipase
  • Human_gene_id: 3991
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3991
  • Human_swiss_prot_no: Q05469
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q05469/entry
  • Mouse_gene_id: 16890
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=16890
  • Mouse_swiss_prot_no: P54310
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P54310
  • Rat_gene_id: 25330
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25330
  • Rat_swiss_prot_no: P15304
  • Rat_swiss_link: http://www.uniprot.org/uniprot/P15304
  • 特异性: HSL Polyclonal Antibody detects endogenous levels of HSL protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: LIPE; Hormone-sensitive lipase; HSL
  • 实测条带: 120kD
  • 信号通路: Insulin Receptor; AMPK
  • 功能: catalytic activity:Diacylglycerol + H(2)O = monoacylglycerol + a carboxylate.,catalytic activity:Monoacylglycerol + H(2)O = glycerol + a carboxylate.,catalytic activity:Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.,enzyme regulation:Rapidly activated by cAMP-dependent phosphorylation under the influence of catecholamines. Dephosphorylation and inactivation are controlled by insulin.,function:In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production.,pathway:Glycerolipid metabolism; triacylglycerol degradation.,similarity:Belongs to the 'GDXG' lipolytic enzyme family.,subcellular location:Found in the high-density caveolae. Translocates to the cytoplasm from the caveolae upon insulin stimulation.,subunit:Interacts with PTRF in the adipocyte cytoplasm.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cell membrane . Membrane, caveola . Cytoplasm, cytosol . Lipid droplet . Found in the high-density caveolae. Translocates to the cytoplasm from the caveolae upon insulin stimulation (PubMed:17026959). Phosphorylation by AMPK reduces its translocation towards the lipid droplets (By similarity). .
  • 组织表达: Testis.
  • tag: hot
  • 科研货号: PLA016391
HSL Polyclonal Antibody
Catalog No PLA016391
Product information
  • 基因名称: LIPE
  • 蛋白名称: Hormone-sensitive lipase
  • Human_gene_id: 3991
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3991
  • Human_swiss_prot_no: Q05469
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q05469/entry
  • Mouse_gene_id: 16890
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=16890
  • Mouse_swiss_prot_no: P54310
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P54310
  • Rat_gene_id: 25330
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25330
  • Rat_swiss_prot_no: P15304
  • Rat_swiss_link: http://www.uniprot.org/uniprot/P15304
  • 特异性: HSL Polyclonal Antibody detects endogenous levels of HSL protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: LIPE; Hormone-sensitive lipase; HSL
  • 实测条带: 120kD
  • 信号通路: Insulin Receptor; AMPK
  • 功能: catalytic activity:Diacylglycerol + H(2)O = monoacylglycerol + a carboxylate.,catalytic activity:Monoacylglycerol + H(2)O = glycerol + a carboxylate.,catalytic activity:Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.,enzyme regulation:Rapidly activated by cAMP-dependent phosphorylation under the influence of catecholamines. Dephosphorylation and inactivation are controlled by insulin.,function:In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production.,pathway:Glycerolipid metabolism; triacylglycerol degradation.,similarity:Belongs to the 'GDXG' lipolytic enzyme family.,subcellular location:Found in the high-density caveolae. Translocates to the cytoplasm from the caveolae upon insulin stimulation.,subunit:Interacts with PTRF in the adipocyte cytoplasm.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cell membrane . Membrane, caveola . Cytoplasm, cytosol . Lipid droplet . Found in the high-density caveolae. Translocates to the cytoplasm from the caveolae upon insulin stimulation (PubMed:17026959). Phosphorylation by AMPK reduces its translocation towards the lipid droplets (By similarity). .
  • 组织表达: Testis.
  • tag: hot
  • 科研货号: PLA016391
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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