hnRNP C1/C2 Polyclonal Antibody

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商品货号： PLA016352

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： HNRNPC
蛋白名称： Heterogeneous nuclear ribonucleoproteins C1/C2
Human_gene_id： 3183
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3183
Human_swiss_prot_no： P07910
Human_swiss_link： http://www.uniprot.org/uniprotkb/P07910/entry
Mouse_gene_id： 15381
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=15381
Mouse_swiss_prot_no： Q9Z204
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9Z204
Rat_swiss_prot_no： P17132
Rat_swiss_link： http://www.uniprot.org/uniprot/P17132
特异性： hnRNP C1/C2 Polyclonal Antibody detects endogenous levels of hnRNP C1/C2 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： HNRNPC; HNRPC; Heterogeneous nuclear ribonucleoproteins C1/C2; hnRNP C1/C2
实测条带： 33kD
信号通路： Spliceosome;
功能： function:Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.,PTM:Phosphorylated on Ser-260 and Ser-299 in resting cells. Phosphorylated on Ser-253 and on 1 serine residue in the poly-Ser stretch at position 238 in response to hydrogen peroxide.,PTM:Sumoylated. Sumoylation reduces affinity for mRNA.,similarity:Belongs to the RRM HNRPC family. RALY subfamily.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subcellular location:Component of ribonucleosomes.,subunit:Tetramer composed of 3 copies of isoform C1 and 1 copy of isoform C2. Assembly of 3 tetramers with bound pre-mRNA gives rise to a 19S complex that interacts with HNRNPA2B1 tetramers. Component of the 40S hnRNP particle. Identified in the spliceosome C complex, at least composed of AQR, ASCC3L1, C19orf29, CDC40, CDC5L, CRNKL1, DDX23, DDX41, DDX48, DDX5, DGCR14, DHX35, DHX38, DHX8, EFTUD2, FRG1, GPATC1, HNRNPA1, HNRNPA2B1, HNRPA3, HNRNPC, HNRPF, HNRPH1, HNRPK, HNRPM, HNRNPR, HNRNPU, KIAA1160, KIAA1604, LSM2, LSM3, MAGOH, MORG1, PABPC1, PLRG1, PNN, PPIE, PPIL1, PPIL3, PPWD1, PRPF19, PRPF4B, PRPF6, PRPF8, RALY, RBM22, RBM8A, RBMX, SART1, SF3A1, SF3A2, SF3A3, SF3B1, SF3B2, SF3B3, SFRS1, SKIV2L2, SNRPA1, SNRPB, SNRPB2, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, SNW1, SRRM1, SRRM2, SYF2, SYNCRIP, TFIP11, THOC4, U2AF1, WDR57, XAB2 and ZCCHC8.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus. Component of ribonucleosomes.
组织表达： Blood vessels- blood vessel,Bone marrow,Brain,Cajal
tag： hot
科研货号： PLA016352

hnRNP C1/C2 Polyclonal Antibody

Catalog No PLA016352

Product information

基因名称： HNRNPC
蛋白名称： Heterogeneous nuclear ribonucleoproteins C1/C2
Human_gene_id： 3183
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3183
Human_swiss_prot_no： P07910
Human_swiss_link： http://www.uniprot.org/uniprotkb/P07910/entry
Mouse_gene_id： 15381
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=15381
Mouse_swiss_prot_no： Q9Z204
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9Z204
Rat_swiss_prot_no： P17132
Rat_swiss_link： http://www.uniprot.org/uniprot/P17132
特异性： hnRNP C1/C2 Polyclonal Antibody detects endogenous levels of hnRNP C1/C2 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： HNRNPC; HNRPC; Heterogeneous nuclear ribonucleoproteins C1/C2; hnRNP C1/C2
实测条带： 33kD
信号通路： Spliceosome;
功能： function:Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.,PTM:Phosphorylated on Ser-260 and Ser-299 in resting cells. Phosphorylated on Ser-253 and on 1 serine residue in the poly-Ser stretch at position 238 in response to hydrogen peroxide.,PTM:Sumoylated. Sumoylation reduces affinity for mRNA.,similarity:Belongs to the RRM HNRPC family. RALY subfamily.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subcellular location:Component of ribonucleosomes.,subunit:Tetramer composed of 3 copies of isoform C1 and 1 copy of isoform C2. Assembly of 3 tetramers with bound pre-mRNA gives rise to a 19S complex that interacts with HNRNPA2B1 tetramers. Component of the 40S hnRNP particle. Identified in the spliceosome C complex, at least composed of AQR, ASCC3L1, C19orf29, CDC40, CDC5L, CRNKL1, DDX23, DDX41, DDX48, DDX5, DGCR14, DHX35, DHX38, DHX8, EFTUD2, FRG1, GPATC1, HNRNPA1, HNRNPA2B1, HNRPA3, HNRNPC, HNRPF, HNRPH1, HNRPK, HNRPM, HNRNPR, HNRNPU, KIAA1160, KIAA1604, LSM2, LSM3, MAGOH, MORG1, PABPC1, PLRG1, PNN, PPIE, PPIL1, PPIL3, PPWD1, PRPF19, PRPF4B, PRPF6, PRPF8, RALY, RBM22, RBM8A, RBMX, SART1, SF3A1, SF3A2, SF3A3, SF3B1, SF3B2, SF3B3, SFRS1, SKIV2L2, SNRPA1, SNRPB, SNRPB2, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, SNW1, SRRM1, SRRM2, SYF2, SYNCRIP, TFIP11, THOC4, U2AF1, WDR57, XAB2 and ZCCHC8.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus. Component of ribonucleosomes.
组织表达： Blood vessels- blood vessel,Bone marrow,Brain,Cajal
tag： hot
科研货号： PLA016352

Hunan UPT Biotechnology Co.,Ltd

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