Histone deacetylase 6 Polyclonal Antibody

> > > >

商品货号： PLA016326

适应性： 人,小鼠

￥600元

规格：

40μL 100μL 200μL

在线咨询

MSDS

说明书

商品描述

基因名称： HDAC6
蛋白名称： Histone deacetylase 6
Human_gene_id： 10013
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10013
Human_swiss_prot_no： Q9UBN7
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9UBN7/entry
Mouse_gene_id： 15185
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=15185
Mouse_swiss_prot_no： Q9Z2V5
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9Z2V5
特异性： Histone deacetylase 6 Polyclonal Antibody detects endogenous levels of Histone deacetylase 6 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： HDAC6; KIAA0901; JM21; Histone deacetylase 6; HD6
实测条带： 135kD
信号通路： Protein_Acetylation
功能： catalytic activity:Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.,function:Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.,PTM:Sumoylated in vitro.,PTM:Ubiquitinated. Its polyubiquitination however does not lead to its degradation.,similarity:Belongs to the histone deacetylase family. Type 2 subfamily.,similarity:Contains 1 UBP-type zinc finger.,subcellular location:It is mainly cytoplasmic, where it is associated with microtubules.,subunit:Interacts with CBFA2T3, HDAC11 and SIRT2. Interacts with F-actin. Interacts with BBIP10.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Cytoplasm, cytoskeleton . Nucleus . Perikaryon . Cell projection, dendrite . Cell projection, axon . It is mainly cytoplasmic, where it is associated with microtubules. .
组织表达： Brain,Epithelium,Kidney,Muscle,Ovary,Placenta,
科研货号： PLA016326

Histone deacetylase 6 Polyclonal Antibody

Catalog No PLA016326

Product information

基因名称： HDAC6
蛋白名称： Histone deacetylase 6
Human_gene_id： 10013
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10013
Human_swiss_prot_no： Q9UBN7
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9UBN7/entry
Mouse_gene_id： 15185
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=15185
Mouse_swiss_prot_no： Q9Z2V5
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9Z2V5
特异性： Histone deacetylase 6 Polyclonal Antibody detects endogenous levels of Histone deacetylase 6 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： HDAC6; KIAA0901; JM21; Histone deacetylase 6; HD6
实测条带： 135kD
信号通路： Protein_Acetylation
功能： catalytic activity:Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.,function:Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.,PTM:Sumoylated in vitro.,PTM:Ubiquitinated. Its polyubiquitination however does not lead to its degradation.,similarity:Belongs to the histone deacetylase family. Type 2 subfamily.,similarity:Contains 1 UBP-type zinc finger.,subcellular location:It is mainly cytoplasmic, where it is associated with microtubules.,subunit:Interacts with CBFA2T3, HDAC11 and SIRT2. Interacts with F-actin. Interacts with BBIP10.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Cytoplasm, cytoskeleton . Nucleus . Perikaryon . Cell projection, dendrite . Cell projection, axon . It is mainly cytoplasmic, where it is associated with microtubules. .
组织表达： Brain,Epithelium,Kidney,Muscle,Ovary,Placenta,
科研货号： PLA016326

Hunan UPT Biotechnology Co.,Ltd

Website：www.uptbio.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.