Histone 1.0 Polyclonal Antibody

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商品货号： PLA016323

适应性： 人,大鼠,小鼠,

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： H1F0
蛋白名称： Histone H1.0
Human_gene_id： 3005
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3005
Human_swiss_prot_no： P07305
Human_swiss_link： http://www.uniprot.org/uniprotkb/P07305/entry
Mouse_swiss_prot_no： P10922
Mouse_swiss_link： http://www.uniprot.org/uniprot/P10922
特异性： Histone 1.0 Polyclonal Antibody detects endogenous levels of Histone 1.0 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： H1F0; H1FV; Histone H1.0; Histone H1'; Histone H1(0)
实测条带： 28kD
信号通路： Protein_Acetylation
功能： function:Histones H1 are necessary for the condensation of nucleosome chains into higher order structures. The H1F0 histones are found in cells that are in terminal stages of differentiation or that have low rates of cell division.,induction:Both the unedited and the RNA edited versions are induced by butyrate (at protein level). Only RNA edited version is induced by DTT, vinblastine or TNF (at protein level).,online information:Histone H1 entry,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR. Phosphorylated on Ser-17 in RNA edited version.,RNA editing:Partially edited. In approximately 3.6% of the mRNA molecules, a new initiator methionine is created by a single uridine insertion in the 5'-UTR, causing an N-terminal extension of 99 amino acids. The existence of the RNA edited version is supported by direct protein sequencing by MS/MS of the following peptides specific to that version: 12-21; 22-33; 37-47; 48-67; 68-83; 84-94 and 97-113. The RNA edited version is called ET-H1.0.,similarity:Belongs to the histone H1/H5 family.,subcellular location:The RNA edited version has been localized to nuclear speckles. During mitosis, it appears in the vicinity of condensed chromosomes.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Chromosome . The RNA edited version has been localized to nuclear speckles. During mitosis, it appears in the vicinity of condensed chromosomes.
组织表达： Colon,Epithelium,Placenta,
科研货号： PLA016323

Histone 1.0 Polyclonal Antibody

Catalog No PLA016323

Product information

基因名称： H1F0
蛋白名称： Histone H1.0
Human_gene_id： 3005
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3005
Human_swiss_prot_no： P07305
Human_swiss_link： http://www.uniprot.org/uniprotkb/P07305/entry
Mouse_swiss_prot_no： P10922
Mouse_swiss_link： http://www.uniprot.org/uniprot/P10922
特异性： Histone 1.0 Polyclonal Antibody detects endogenous levels of Histone 1.0 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： H1F0; H1FV; Histone H1.0; Histone H1'; Histone H1(0)
实测条带： 28kD
信号通路： Protein_Acetylation
功能： function:Histones H1 are necessary for the condensation of nucleosome chains into higher order structures. The H1F0 histones are found in cells that are in terminal stages of differentiation or that have low rates of cell division.,induction:Both the unedited and the RNA edited versions are induced by butyrate (at protein level). Only RNA edited version is induced by DTT, vinblastine or TNF (at protein level).,online information:Histone H1 entry,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR. Phosphorylated on Ser-17 in RNA edited version.,RNA editing:Partially edited. In approximately 3.6% of the mRNA molecules, a new initiator methionine is created by a single uridine insertion in the 5'-UTR, causing an N-terminal extension of 99 amino acids. The existence of the RNA edited version is supported by direct protein sequencing by MS/MS of the following peptides specific to that version: 12-21; 22-33; 37-47; 48-67; 68-83; 84-94 and 97-113. The RNA edited version is called ET-H1.0.,similarity:Belongs to the histone H1/H5 family.,subcellular location:The RNA edited version has been localized to nuclear speckles. During mitosis, it appears in the vicinity of condensed chromosomes.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Chromosome . The RNA edited version has been localized to nuclear speckles. During mitosis, it appears in the vicinity of condensed chromosomes.
组织表达： Colon,Epithelium,Placenta,
科研货号： PLA016323

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