Histamine H3 Receptor Polyclonal Antibody

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商品货号： PLA016321

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： HRH3
蛋白名称： Histamine H3 receptor
Human_gene_id： 11255
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11255
Human_swiss_prot_no： Q9Y5N1
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9Y5N1/entry
Mouse_gene_id： 99296
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=99296
Mouse_swiss_prot_no： P58406
Mouse_swiss_link： http://www.uniprot.org/uniprot/P58406
Rat_gene_id： 85268
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=85268
Rat_swiss_prot_no： Q9QYN8
Rat_swiss_link： http://www.uniprot.org/uniprot/Q9QYN8
特异性： Histamine H3 Receptor Polyclonal Antibody detects endogenous levels of Histamine H3 Receptor protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： HRH3; GPCR97; Histamine H3 receptor; H3R; HH3R; G-protein coupled receptor 97
实测条带： 49kD
信号通路： Neuroactive ligand-receptor interaction;
功能： alternative products:Additional isoforms seem to exist,function:The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist). Agonist stimulation of isoform 3 niether modified adenylate cyclase activity nor induced intracellular calcium mobilization.,miscellaneous:Does not bind to cimetidine and tripolidine. Shows modest affinity for thioperamide, imetit, N-alpha-methylhistamine and R(-)-alpha-methylhistamine. Isoform 4 is unable to bind to iodoproxyfan while isoforms 1 and 3 bind it with high affinity.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed predominantly in the CNS, with the greatest expression in the thalamus and caudate nucleus. The various isoforms are mainly coexpressed in brain, but their relative expression level varies in a region-specific manner. Isoform 3 and isoform 7 are highly expressed in the thalamus, caudate nucleus and cerebellum while isoform 5 and isoform 6 show a poor expression. Isoform 5 and isoform 6 show a high expression in the amygdala, substantia nigra, cerebral cortex and hypothalamus. Isoform 7 is not found in hypothalamus or substantia nigra.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane; Multi-pass membrane protein.
组织表达： Expressed predominantly in the CNS, with the greatest expression in the thalamus and caudate nucleus. The various isoforms are mainly coexpressed in brain, but their relative expression level varies in a region-specific manner. Isoform 3 and isoform 7 are highly expressed in the thalamus, caudate nucleus and cerebellum while isoform 5 and isoform 6 show a poor expression. Isoform 5 and isoform 6 show a high expression in the amygdala, substantia nigra, cerebral cortex and hypothalamus. Isoform 7 is not found in hypothalamus or substantia nigra.
科研货号： PLA016321

Histamine H3 Receptor Polyclonal Antibody

Catalog No PLA016321

Product information

基因名称： HRH3
蛋白名称： Histamine H3 receptor
Human_gene_id： 11255
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11255
Human_swiss_prot_no： Q9Y5N1
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9Y5N1/entry
Mouse_gene_id： 99296
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=99296
Mouse_swiss_prot_no： P58406
Mouse_swiss_link： http://www.uniprot.org/uniprot/P58406
Rat_gene_id： 85268
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=85268
Rat_swiss_prot_no： Q9QYN8
Rat_swiss_link： http://www.uniprot.org/uniprot/Q9QYN8
特异性： Histamine H3 Receptor Polyclonal Antibody detects endogenous levels of Histamine H3 Receptor protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： HRH3; GPCR97; Histamine H3 receptor; H3R; HH3R; G-protein coupled receptor 97
实测条带： 49kD
信号通路： Neuroactive ligand-receptor interaction;
功能： alternative products:Additional isoforms seem to exist,function:The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist). Agonist stimulation of isoform 3 niether modified adenylate cyclase activity nor induced intracellular calcium mobilization.,miscellaneous:Does not bind to cimetidine and tripolidine. Shows modest affinity for thioperamide, imetit, N-alpha-methylhistamine and R(-)-alpha-methylhistamine. Isoform 4 is unable to bind to iodoproxyfan while isoforms 1 and 3 bind it with high affinity.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed predominantly in the CNS, with the greatest expression in the thalamus and caudate nucleus. The various isoforms are mainly coexpressed in brain, but their relative expression level varies in a region-specific manner. Isoform 3 and isoform 7 are highly expressed in the thalamus, caudate nucleus and cerebellum while isoform 5 and isoform 6 show a poor expression. Isoform 5 and isoform 6 show a high expression in the amygdala, substantia nigra, cerebral cortex and hypothalamus. Isoform 7 is not found in hypothalamus or substantia nigra.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane; Multi-pass membrane protein.
组织表达： Expressed predominantly in the CNS, with the greatest expression in the thalamus and caudate nucleus. The various isoforms are mainly coexpressed in brain, but their relative expression level varies in a region-specific manner. Isoform 3 and isoform 7 are highly expressed in the thalamus, caudate nucleus and cerebellum while isoform 5 and isoform 6 show a poor expression. Isoform 5 and isoform 6 show a high expression in the amygdala, substantia nigra, cerebral cortex and hypothalamus. Isoform 7 is not found in hypothalamus or substantia nigra.
科研货号： PLA016321

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