GRB14 Polyclonal Antibody

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商品货号： PLA016241

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： GRB14
蛋白名称： Growth factor receptor-bound protein 14
Human_gene_id： 2888
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2888
Human_swiss_prot_no： Q14449
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q14449/entry
Mouse_gene_id： 50915
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=50915
Mouse_swiss_prot_no： Q9JLM9
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9JLM9
Rat_gene_id： 58844
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=58844
Rat_swiss_prot_no： O88900
Rat_swiss_link： http://www.uniprot.org/uniprot/O88900
特异性： GRB14 Polyclonal Antibody detects endogenous levels of GRB14 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： GRB14; Growth factor receptor-bound protein 14; GRB14 adapter protein
实测条带： 61kD
信号通路： Stem cell pathway
功能： function:Interacts with the cytoplasmic domain of the autophosphorylated insulin receptor which is then inhibited. The interaction is mediated by the SH2 domain.,PTM:Phosphorylated on serine residues.,similarity:Belongs to the GRB7/10/14 family.,similarity:Contains 1 PH domain.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 SH2 domain.,subunit:Binds to the ankyrin repeat region of TNKS2 via its N-terminus.,tissue specificity:Expressed at high levels in the liver, kidney, pancreas, testis, ovary, heart and skeletal muscle.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Endosome membrane ; Peripheral membrane protein . Upon insulin stimulation, translocates to the plasma membrane. .
组织表达： Expressed at high levels in the liver, kidney, pancreas, testis, ovary, heart and skeletal muscle.
科研货号： PLA016241

GRB14 Polyclonal Antibody

Catalog No PLA016241

Product information

基因名称： GRB14
蛋白名称： Growth factor receptor-bound protein 14
Human_gene_id： 2888
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2888
Human_swiss_prot_no： Q14449
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q14449/entry
Mouse_gene_id： 50915
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=50915
Mouse_swiss_prot_no： Q9JLM9
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9JLM9
Rat_gene_id： 58844
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=58844
Rat_swiss_prot_no： O88900
Rat_swiss_link： http://www.uniprot.org/uniprot/O88900
特异性： GRB14 Polyclonal Antibody detects endogenous levels of GRB14 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： GRB14; Growth factor receptor-bound protein 14; GRB14 adapter protein
实测条带： 61kD
信号通路： Stem cell pathway
功能： function:Interacts with the cytoplasmic domain of the autophosphorylated insulin receptor which is then inhibited. The interaction is mediated by the SH2 domain.,PTM:Phosphorylated on serine residues.,similarity:Belongs to the GRB7/10/14 family.,similarity:Contains 1 PH domain.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 SH2 domain.,subunit:Binds to the ankyrin repeat region of TNKS2 via its N-terminus.,tissue specificity:Expressed at high levels in the liver, kidney, pancreas, testis, ovary, heart and skeletal muscle.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Endosome membrane ; Peripheral membrane protein . Upon insulin stimulation, translocates to the plasma membrane. .
组织表达： Expressed at high levels in the liver, kidney, pancreas, testis, ovary, heart and skeletal muscle.
科研货号： PLA016241

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