其他名称: GORASP2; GOLPH6; Golgi reassembly-stacking protein 2; GRS2; Golgi phosphoprotein 6; GOLPH6; Golgi reassembly-stacking protein of 55 kDa; GRASP55; p59
实测条带: 47kD
功能: function:May be involved in assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after mitotic breakdown. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane Tgfa.,PTM:Myristoylated. Myristoylation is essential for the Golgi targeting.,PTM:Palmitoylated.,PTM:Phosphorylated in mitotic cells.,similarity:Belongs to the GORASP family.,similarity:Contains 1 PDZ (DHR) domain.,subunit:Forms a RAB2 effector complex with BLZF1/Golgin 45 in the medial Golgi. Interacts with members of the p24 cargo receptors. Interacts with CNIH and the cytoplasmic domain of transmembrane TGFA, prior its transit in the trans-Golgi. Does not interact with GM130.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Golgi apparatus membrane ; Lipid-anchor . Endoplasmic reticulum membrane . Golgi apparatus . Detected in the intermediate Golgi, membrane-associated (By similarity). ER stress triggers its relocalization from Golgi to ER membrane (PubMed:27062250, PubMed:28067262). .
其他名称: GORASP2; GOLPH6; Golgi reassembly-stacking protein 2; GRS2; Golgi phosphoprotein 6; GOLPH6; Golgi reassembly-stacking protein of 55 kDa; GRASP55; p59
实测条带: 47kD
功能: function:May be involved in assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after mitotic breakdown. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane Tgfa.,PTM:Myristoylated. Myristoylation is essential for the Golgi targeting.,PTM:Palmitoylated.,PTM:Phosphorylated in mitotic cells.,similarity:Belongs to the GORASP family.,similarity:Contains 1 PDZ (DHR) domain.,subunit:Forms a RAB2 effector complex with BLZF1/Golgin 45 in the medial Golgi. Interacts with members of the p24 cargo receptors. Interacts with CNIH and the cytoplasmic domain of transmembrane TGFA, prior its transit in the trans-Golgi. Does not interact with GM130.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Golgi apparatus membrane ; Lipid-anchor . Endoplasmic reticulum membrane . Golgi apparatus . Detected in the intermediate Golgi, membrane-associated (By similarity). ER stress triggers its relocalization from Golgi to ER membrane (PubMed:27062250, PubMed:28067262). .