功能： function:Couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.,similarity:Belongs to the GRB2/sem-5/DRK family.,similarity:Contains 1 SH2 domain.,similarity:Contains 2 SH3 domains.,subunit:Associates through its SH2 domain with ligand-activated receptors for stem cell factor (KIT) and erythropoietin (EPOR). Also forms a stable complex with the Bcr-Abl oncoprotein. GRAP is associated with the Ras guanine nucleotide exchange factor SOS1, primarily through its N-terminal SH3 domain. Interacts with phosphorylated LAT upon TCR activation. Interacts with SHB.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Membrane ; Peripheral membrane protein . Cell junction, synapse . Localizes at the presynaptic terminal. .
功能： function:Couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.,similarity:Belongs to the GRB2/sem-5/DRK family.,similarity:Contains 1 SH2 domain.,similarity:Contains 2 SH3 domains.,subunit:Associates through its SH2 domain with ligand-activated receptors for stem cell factor (KIT) and erythropoietin (EPOR). Also forms a stable complex with the Bcr-Abl oncoprotein. GRAP is associated with the Ras guanine nucleotide exchange factor SOS1, primarily through its N-terminal SH3 domain. Interacts with phosphorylated LAT upon TCR activation. Interacts with SHB.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Membrane ; Peripheral membrane protein . Cell junction, synapse . Localizes at the presynaptic terminal. .
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