Glucuronidase β Polyclonal Antibody

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商品货号： PLA016126

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： GUSB
蛋白名称： Beta-glucuronidase
Human_gene_id： 2990
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2990
Human_swiss_prot_no： P08236
Human_swiss_link： http://www.uniprot.org/uniprotkb/P08236/entry
Mouse_gene_id： 110006
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=110006
Mouse_swiss_prot_no： P12265
Mouse_swiss_link： http://www.uniprot.org/uniprot/P12265
Rat_gene_id： 24434
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24434
Rat_swiss_prot_no： P06760
Rat_swiss_link： http://www.uniprot.org/uniprot/P06760
特异性： Glucuronidase β Polyclonal Antibody detects endogenous levels of Glucuronidase β protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： IHC-p: 100-300.WB 1:500 - 1:2000. ELISA: 1:10000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： GUSB; Beta-glucuronidase; Beta-G1
实测条带： 78kD
信号通路： Pentose and glucuronate interconversions;Starch and sucrose metabolism;Glycosaminoglycan degradation;Porphyrin and chlorophyll metabolism;Drug metabolism;Lysosome;
功能： catalytic activity:A beta-D-glucuronoside + H(2)O = D-glucuronate + an alcohol.,disease:Defects in GUSB are the cause of mucopolysaccharidosis type 7 (MPS7) [MIM:253220]; also known as Sly syndrome. MPS7 is an autosomal recessive lysosomal storage disease characterized by inability to degrade glucuronic acid-containing glycosaminoglycans. The phenotype is highly variable, ranging from severe lethal hydrops fetalis to mild forms with survival into adulthood. Most patients with the intermediate phenotype show hepatomegaly, skeletal anomalies, coarse facies, and variable degrees of mental impairment.,disease:Mucopolysaccharidosis type 7 is associated with non-immune hydrops fetalis [MIM:236750]. Hydrops fetalis is a generalized edema of the fetus with fluid accumulation in the body cavities.,enzyme regulation:Inhibited by L-aspartic acid.,function:Plays an important role in the degradation of dermatan and keratan sulfates.,PTM:N-linked glycosylated with 3 to 4 oligosaccharide chains.,similarity:Belongs to the glycosyl hydrolase 2 family.,subunit:Homotetramer.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Lysosome.
组织表达： Colon,Fibroblast,Liver,Placenta,Plasma,
科研货号： PLA016126

Glucuronidase β Polyclonal Antibody

Catalog No PLA016126

Product information

基因名称： GUSB
蛋白名称： Beta-glucuronidase
Human_gene_id： 2990
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2990
Human_swiss_prot_no： P08236
Human_swiss_link： http://www.uniprot.org/uniprotkb/P08236/entry
Mouse_gene_id： 110006
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=110006
Mouse_swiss_prot_no： P12265
Mouse_swiss_link： http://www.uniprot.org/uniprot/P12265
Rat_gene_id： 24434
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24434
Rat_swiss_prot_no： P06760
Rat_swiss_link： http://www.uniprot.org/uniprot/P06760
特异性： Glucuronidase β Polyclonal Antibody detects endogenous levels of Glucuronidase β protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： IHC-p: 100-300.WB 1:500 - 1:2000. ELISA: 1:10000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： GUSB; Beta-glucuronidase; Beta-G1
实测条带： 78kD
信号通路： Pentose and glucuronate interconversions;Starch and sucrose metabolism;Glycosaminoglycan degradation;Porphyrin and chlorophyll metabolism;Drug metabolism;Lysosome;
功能： catalytic activity:A beta-D-glucuronoside + H(2)O = D-glucuronate + an alcohol.,disease:Defects in GUSB are the cause of mucopolysaccharidosis type 7 (MPS7) [MIM:253220]; also known as Sly syndrome. MPS7 is an autosomal recessive lysosomal storage disease characterized by inability to degrade glucuronic acid-containing glycosaminoglycans. The phenotype is highly variable, ranging from severe lethal hydrops fetalis to mild forms with survival into adulthood. Most patients with the intermediate phenotype show hepatomegaly, skeletal anomalies, coarse facies, and variable degrees of mental impairment.,disease:Mucopolysaccharidosis type 7 is associated with non-immune hydrops fetalis [MIM:236750]. Hydrops fetalis is a generalized edema of the fetus with fluid accumulation in the body cavities.,enzyme regulation:Inhibited by L-aspartic acid.,function:Plays an important role in the degradation of dermatan and keratan sulfates.,PTM:N-linked glycosylated with 3 to 4 oligosaccharide chains.,similarity:Belongs to the glycosyl hydrolase 2 family.,subunit:Homotetramer.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Lysosome.
组织表达： Colon,Fibroblast,Liver,Placenta,Plasma,
科研货号： PLA016126

Hunan UPT Biotechnology Co.,Ltd

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