功能： disease:Defects in GHRHR are a cause of isolated growth hormone deficiency type IB (IGHD IB) [MIM:262400]; also known as pituitary dwarfism I. IGHD IB is an autosomal recessive deficiency of GH which cause short stature.,function:Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion.,similarity:Belongs to the G-protein coupled receptor 2 family.,tissue specificity:Pituitary gland.,
功能： disease:Defects in GHRHR are a cause of isolated growth hormone deficiency type IB (IGHD IB) [MIM:262400]; also known as pituitary dwarfism I. IGHD IB is an autosomal recessive deficiency of GH which cause short stature.,function:Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion.,similarity:Belongs to the G-protein coupled receptor 2 family.,tissue specificity:Pituitary gland.,
在线咨询
湘公网安备