其他名称： EPN2; KIAA1065; Epsin-2; EPS-15-interacting protein 2
实测条带： 68kD
信号通路： Endocytosis;
功能： caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,domain:The DPW repeat domain is involved in AP-2 and clathrin binding.,domain:The NPF repeat domain is involved in EPS15 binding.,function:Plays a role in the formation of clathrin-coated invaginations and endocytosis.,PTM:Ubiquitinated.,similarity:Belongs to the epsin family.,similarity:Contains 1 ENTH (epsin N-terminal homology) domain.,similarity:Contains 2 UIM (ubiquitin-interacting motif) repeats.,subcellular location:In punctate structures throughout the cell, associated with clathrin-coated vesicles, and particularly concentrated in the region of the Golgi complex.,subunit:Binds EPS15 (By similarity). Binds AP-2 and clathrin.,tissue specificity:Highest expression is found in brain. Detected at lower levels in lung and liver.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Cytoplasmic vesicle, clathrin-coated vesicle . In punctate structures throughout the cell, associated with clathrin-coated vesicles, and particularly concentrated in the region of the Golgi complex.
组织表达： Highest expression is found in brain. Detected at lower levels in lung and liver.
其他名称： EPN2; KIAA1065; Epsin-2; EPS-15-interacting protein 2
实测条带： 68kD
信号通路： Endocytosis;
功能： caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,domain:The DPW repeat domain is involved in AP-2 and clathrin binding.,domain:The NPF repeat domain is involved in EPS15 binding.,function:Plays a role in the formation of clathrin-coated invaginations and endocytosis.,PTM:Ubiquitinated.,similarity:Belongs to the epsin family.,similarity:Contains 1 ENTH (epsin N-terminal homology) domain.,similarity:Contains 2 UIM (ubiquitin-interacting motif) repeats.,subcellular location:In punctate structures throughout the cell, associated with clathrin-coated vesicles, and particularly concentrated in the region of the Golgi complex.,subunit:Binds EPS15 (By similarity). Binds AP-2 and clathrin.,tissue specificity:Highest expression is found in brain. Detected at lower levels in lung and liver.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Cytoplasmic vesicle, clathrin-coated vesicle . In punctate structures throughout the cell, associated with clathrin-coated vesicles, and particularly concentrated in the region of the Golgi complex.
组织表达： Highest expression is found in brain. Detected at lower levels in lung and liver.
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