DNA pol β Polyclonal Antibody

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商品货号： PLA015669

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： POLB
蛋白名称： DNA polymerase beta
Human_gene_id： 5423
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5423
Human_swiss_prot_no： P06746
Human_swiss_link： http://www.uniprot.org/uniprotkb/P06746/entry
Mouse_gene_id： 18970
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18970
Mouse_swiss_prot_no： Q8K409
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q8K409
Rat_gene_id： 29240
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29240
Rat_swiss_prot_no： P06766
Rat_swiss_link： http://www.uniprot.org/uniprot/P06766
特异性： DNA pol β Polyclonal Antibody detects endogenous levels of DNA pol β protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： POLB; DNA polymerase beta
实测条带： 38kD
信号通路： Base excision repair;
功能： catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,cofactor:Binds 2 magnesium ions per subunit.,domain:Residues 239-252 form a flexible loop which appears to affect the polymerase fidelity.,function:Repair polymerase. Conducts "gap-filling" DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.,PTM:Methylation by PRMT6 stimulates the polymerase activity by enhancing DNA binding and processivity.,similarity:Belongs to the DNA polymerase type-X family.,subunit:Monomer.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus. Cytoplasm. Cytoplasmic in normal conditions. Translocates to the nucleus following DNA damage.
组织表达： Skin,Testis,
科研货号： PLA015669

DNA pol β Polyclonal Antibody

Catalog No PLA015669

Product information

基因名称： POLB
蛋白名称： DNA polymerase beta
Human_gene_id： 5423
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5423
Human_swiss_prot_no： P06746
Human_swiss_link： http://www.uniprot.org/uniprotkb/P06746/entry
Mouse_gene_id： 18970
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18970
Mouse_swiss_prot_no： Q8K409
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q8K409
Rat_gene_id： 29240
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29240
Rat_swiss_prot_no： P06766
Rat_swiss_link： http://www.uniprot.org/uniprot/P06766
特异性： DNA pol β Polyclonal Antibody detects endogenous levels of DNA pol β protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： POLB; DNA polymerase beta
实测条带： 38kD
信号通路： Base excision repair;
功能： catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,cofactor:Binds 2 magnesium ions per subunit.,domain:Residues 239-252 form a flexible loop which appears to affect the polymerase fidelity.,function:Repair polymerase. Conducts "gap-filling" DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.,PTM:Methylation by PRMT6 stimulates the polymerase activity by enhancing DNA binding and processivity.,similarity:Belongs to the DNA polymerase type-X family.,subunit:Monomer.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus. Cytoplasm. Cytoplasmic in normal conditions. Translocates to the nucleus following DNA damage.
组织表达： Skin,Testis,
科研货号： PLA015669

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