DIO3 Polyclonal Antibody

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商品货号： PLA015652

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： DIO3
蛋白名称： Type III iodothyronine deiodinase
Human_gene_id： 1735
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1735
Human_swiss_prot_no： P55073
Human_swiss_link： http://www.uniprot.org/uniprotkb/P55073/entry
Mouse_gene_id： 107585
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=107585
Mouse_swiss_prot_no： Q91ZI8
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q91ZI8
Rat_gene_id： 29475
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29475
Rat_swiss_prot_no： P49897
Rat_swiss_link： http://www.uniprot.org/uniprot/P49897
特异性： DIO3 Polyclonal Antibody detects endogenous levels of DIO3 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： DIO3; ITDI3; TXDI3; Type III iodothyronine deiodinase; 5DIII; DIOIII; Type 3 DI; Type-III 5'-deiodinase
实测条带： 31kD
功能： catalytic activity:3,3',5'-triiodo-L-thyronine + iodide + A + H(+) = L-thyroxine + AH(2).,function:Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during embryological development.,function:Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).,similarity:Belongs to the iodothyronine deiodinase family.,tissue specificity:Expressed in placenta and several fetal tissues.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane ; Single-pass type II membrane protein . Endosome membrane ; Single-pass type II membrane protein .
组织表达： Expressed in placenta and several fetal tissues.
科研货号： PLA015652

DIO3 Polyclonal Antibody

Catalog No PLA015652

Product information

基因名称： DIO3
蛋白名称： Type III iodothyronine deiodinase
Human_gene_id： 1735
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1735
Human_swiss_prot_no： P55073
Human_swiss_link： http://www.uniprot.org/uniprotkb/P55073/entry
Mouse_gene_id： 107585
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=107585
Mouse_swiss_prot_no： Q91ZI8
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q91ZI8
Rat_gene_id： 29475
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29475
Rat_swiss_prot_no： P49897
Rat_swiss_link： http://www.uniprot.org/uniprot/P49897
特异性： DIO3 Polyclonal Antibody detects endogenous levels of DIO3 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： DIO3; ITDI3; TXDI3; Type III iodothyronine deiodinase; 5DIII; DIOIII; Type 3 DI; Type-III 5'-deiodinase
实测条带： 31kD
功能： catalytic activity:3,3',5'-triiodo-L-thyronine + iodide + A + H(+) = L-thyroxine + AH(2).,function:Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during embryological development.,function:Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).,similarity:Belongs to the iodothyronine deiodinase family.,tissue specificity:Expressed in placenta and several fetal tissues.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane ; Single-pass type II membrane protein . Endosome membrane ; Single-pass type II membrane protein .
组织表达： Expressed in placenta and several fetal tissues.
科研货号： PLA015652

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