Cytokeratin 20 Polyclonal Antibody

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商品货号： PLA015575

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： KRT20
蛋白名称： Keratin type I cytoskeletal 20
Human_gene_id： 54474
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54474
Human_swiss_prot_no： P35900
Human_swiss_link： http://www.uniprot.org/uniprotkb/P35900/entry
Mouse_gene_id： 66809
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=66809
Mouse_swiss_prot_no： Q9D312
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9D312
Rat_gene_id： 286912
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=286912
Rat_swiss_prot_no： P25030
Rat_swiss_link： http://www.uniprot.org/uniprot/P25030
特异性： Cytokeratin 20 Polyclonal Antibody detects endogenous levels of Cytokeratin 20 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： KRT20; Keratin; type I cytoskeletal 20; Cytokeratin-20; CK-20; Keratin-20; K20; Protein IT
实测条带： 49kD
功能： developmental stage:First detected at embryonic week 8 in individual 'converted' simple epithelial cells of the developing intestinal mucosa. In later fetal stages, synthesis extends over most goblet cells and a variable number of villus enterocytes. In the developing gastric and intestinal mucosa, expressed in all enterocytes and goblet cells as well as certain 'low-differentiated' columnar cells, whereas the neuroendocrine and Paneth cells are negative.,function:Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine.,miscellaneous:There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).,PTM:Hyperphosphorylation at Ser-13 occurs during the early stages of apoptosis but becomes less prominent during the later stages. Phosphorylation at Ser-13 also increases in response to stress brought on by cell injury.,PTM:Proteolytically cleaved by caspases during apoptosis. Cleavage occurs at Asp-228.,similarity:Belongs to the intermediate filament family.,subunit:Heterotetramer of two type I and two type II keratins. Associates with KRT8.,tissue specificity:Expressed predominantly in the intestinal epithelium. Expressed in luminal cells of colonic mucosa. Also expressed in the Merkel cells of keratinized oral mucosa; specifically at the tips of some rete ridges of the gingival mucosa, in the basal layer of the palatal mucosa and in the taste buds of lingual mucosa.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm .
组织表达： Expressed predominantly in the intestinal epithelium. Expressed in luminal cells of colonic mucosa. Also expressed in the Merkel cells of keratinized oral mucosa; specifically at the tips of some rete ridges of the gingival mucosa, in the basal layer of the palatal mucosa and in the taste buds of lingual mucosa.
tag： hot
科研货号： PLA015575

Cytokeratin 20 Polyclonal Antibody

Catalog No PLA015575

Product information

基因名称： KRT20
蛋白名称： Keratin type I cytoskeletal 20
Human_gene_id： 54474
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54474
Human_swiss_prot_no： P35900
Human_swiss_link： http://www.uniprot.org/uniprotkb/P35900/entry
Mouse_gene_id： 66809
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=66809
Mouse_swiss_prot_no： Q9D312
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9D312
Rat_gene_id： 286912
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=286912
Rat_swiss_prot_no： P25030
Rat_swiss_link： http://www.uniprot.org/uniprot/P25030
特异性： Cytokeratin 20 Polyclonal Antibody detects endogenous levels of Cytokeratin 20 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： KRT20; Keratin; type I cytoskeletal 20; Cytokeratin-20; CK-20; Keratin-20; K20; Protein IT
实测条带： 49kD
功能： developmental stage:First detected at embryonic week 8 in individual 'converted' simple epithelial cells of the developing intestinal mucosa. In later fetal stages, synthesis extends over most goblet cells and a variable number of villus enterocytes. In the developing gastric and intestinal mucosa, expressed in all enterocytes and goblet cells as well as certain 'low-differentiated' columnar cells, whereas the neuroendocrine and Paneth cells are negative.,function:Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine.,miscellaneous:There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).,PTM:Hyperphosphorylation at Ser-13 occurs during the early stages of apoptosis but becomes less prominent during the later stages. Phosphorylation at Ser-13 also increases in response to stress brought on by cell injury.,PTM:Proteolytically cleaved by caspases during apoptosis. Cleavage occurs at Asp-228.,similarity:Belongs to the intermediate filament family.,subunit:Heterotetramer of two type I and two type II keratins. Associates with KRT8.,tissue specificity:Expressed predominantly in the intestinal epithelium. Expressed in luminal cells of colonic mucosa. Also expressed in the Merkel cells of keratinized oral mucosa; specifically at the tips of some rete ridges of the gingival mucosa, in the basal layer of the palatal mucosa and in the taste buds of lingual mucosa.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm .
组织表达： Expressed predominantly in the intestinal epithelium. Expressed in luminal cells of colonic mucosa. Also expressed in the Merkel cells of keratinized oral mucosa; specifically at the tips of some rete ridges of the gingival mucosa, in the basal layer of the palatal mucosa and in the taste buds of lingual mucosa.
tag： hot
科研货号： PLA015575

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