CYP8B1 Polyclonal Antibody

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商品货号： PLA015550

适应性： 人,小鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： CYP8B1
蛋白名称： 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase
Human_gene_id： 1582
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1582
Human_swiss_prot_no： Q9UNU6
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9UNU6/entry
Mouse_gene_id： 13124
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=13124
Mouse_swiss_prot_no： O88962
Mouse_swiss_link： http://www.uniprot.org/uniprot/O88962
特异性： CYP8B1 Polyclonal Antibody detects endogenous levels of CYP8B1 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CYP8B1; CYP12; 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase; 7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase; CYPVIIIB1; Cytochrome P450 8B1; Sterol 12-alpha-hydroxylase
实测条带： 58kD
信号通路： Primary bile acid biosynthesis;PPAR;
功能： catalytic activity:7-alpha-hydroxycholest-4-en-3-one + NADPH + O(2) = 7-alpha,12-alpha-dihydroxycholest-4-en-3-one + NADP(+) + H(2)O.,cofactor:Heme group.,function:Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha-dihydroxy-4-cholesten-3-one. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. Has a rather broad substrate specificity including a number of 7-alpha-hydroxylated C27 steroids.,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Liver.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Endoplasmic reticulum membrane ; Single-pass membrane protein . Microsome membrane ; Single-pass membrane protein .
组织表达： Liver.
科研货号： PLA015550

CYP8B1 Polyclonal Antibody

Catalog No PLA015550

Product information

基因名称： CYP8B1
蛋白名称： 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase
Human_gene_id： 1582
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1582
Human_swiss_prot_no： Q9UNU6
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9UNU6/entry
Mouse_gene_id： 13124
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=13124
Mouse_swiss_prot_no： O88962
Mouse_swiss_link： http://www.uniprot.org/uniprot/O88962
特异性： CYP8B1 Polyclonal Antibody detects endogenous levels of CYP8B1 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CYP8B1; CYP12; 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase; 7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase; CYPVIIIB1; Cytochrome P450 8B1; Sterol 12-alpha-hydroxylase
实测条带： 58kD
信号通路： Primary bile acid biosynthesis;PPAR;
功能： catalytic activity:7-alpha-hydroxycholest-4-en-3-one + NADPH + O(2) = 7-alpha,12-alpha-dihydroxycholest-4-en-3-one + NADP(+) + H(2)O.,cofactor:Heme group.,function:Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha-dihydroxy-4-cholesten-3-one. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. Has a rather broad substrate specificity including a number of 7-alpha-hydroxylated C27 steroids.,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Liver.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Endoplasmic reticulum membrane ; Single-pass membrane protein . Microsome membrane ; Single-pass membrane protein .
组织表达： Liver.
科研货号： PLA015550

Hunan UPT Biotechnology Co.,Ltd

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E-mail：service@uptbio.com

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