Cyclin L1 Polyclonal Antibody

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商品货号： PLA015497

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： CCNL1
蛋白名称： Cyclin-L1
Human_gene_id： 57018
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57018
Human_swiss_prot_no： Q9UK58
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9UK58/entry
Mouse_gene_id： 56706
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56706
Mouse_swiss_prot_no： Q52KE7
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q52KE7
Rat_gene_id： 1.0091e+008
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=100909712
Rat_swiss_prot_no： Q9R1Q2
Rat_swiss_link： http://www.uniprot.org/uniprot/Q9R1Q2
特异性： Cyclin L1 Polyclonal Antibody detects endogenous levels of Cyclin L1 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CCNL1; BM-001; Cyclin-L1; Cyclin-L
实测条带： 60kD
功能： alternative products:Ccnl1 is an immediate-early gene with independently regulated isoforms,domain:Contains a RS region (arginine-serine dipeptide repeat) within the C-terminal domain which is the hallmark of the SR family of splicing factors. This region probably plays a role in protein-protein interactions.,function:Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Seems to be involved in the regulation of RNA polymerase II (pol II). Functions in association with cyclin-dependent kinases (CDKs) and has a role in the second step of splicing. May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). Inhibited by the CDK-specific inhibitor p21.,miscellaneous:CCNL1 is amplified in several HNSCC. May play a critical role in the formation of loco-regional metastases and an unfavorable clinical outcome of HNSCC.,sequence caution:Probable cloning artifact.,similarity:Belongs to the cyclin family. Cyclin L subfamily.,subcellular location:More specifically found in nuclear intrachromatin granules clusters (IGC), also called nuclear speckles, which are storage compartments for nuclear proteins involved in mRNA processing.,subunit:Interacts with POLR2A via its hyperphosphorylated C-terminal domain (CTD) (By similarity). Interacts with CDC2L1 or CDC2L2, and SFRS2.,tissue specificity:Ubiquitous with higher level in thymus. Overexpression in primary tumors of head and neck squamous cell carcinomas (HNSCC).,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus speckle . Nucleus, nucleoplasm . Found in nuclear intrachromatin granules clusters (IGC), also called nuclear speckles, which are storage compartments for nuclear proteins involved in mRNA processing. .
组织表达： Widely expressed. Overexpression in primary tumors of head and neck squamous cell carcinomas (HNSCC).
科研货号： PLA015497

Cyclin L1 Polyclonal Antibody

Catalog No PLA015497

Product information

基因名称： CCNL1
蛋白名称： Cyclin-L1
Human_gene_id： 57018
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57018
Human_swiss_prot_no： Q9UK58
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9UK58/entry
Mouse_gene_id： 56706
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56706
Mouse_swiss_prot_no： Q52KE7
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q52KE7
Rat_gene_id： 1.0091e+008
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=100909712
Rat_swiss_prot_no： Q9R1Q2
Rat_swiss_link： http://www.uniprot.org/uniprot/Q9R1Q2
特异性： Cyclin L1 Polyclonal Antibody detects endogenous levels of Cyclin L1 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CCNL1; BM-001; Cyclin-L1; Cyclin-L
实测条带： 60kD
功能： alternative products:Ccnl1 is an immediate-early gene with independently regulated isoforms,domain:Contains a RS region (arginine-serine dipeptide repeat) within the C-terminal domain which is the hallmark of the SR family of splicing factors. This region probably plays a role in protein-protein interactions.,function:Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Seems to be involved in the regulation of RNA polymerase II (pol II). Functions in association with cyclin-dependent kinases (CDKs) and has a role in the second step of splicing. May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). Inhibited by the CDK-specific inhibitor p21.,miscellaneous:CCNL1 is amplified in several HNSCC. May play a critical role in the formation of loco-regional metastases and an unfavorable clinical outcome of HNSCC.,sequence caution:Probable cloning artifact.,similarity:Belongs to the cyclin family. Cyclin L subfamily.,subcellular location:More specifically found in nuclear intrachromatin granules clusters (IGC), also called nuclear speckles, which are storage compartments for nuclear proteins involved in mRNA processing.,subunit:Interacts with POLR2A via its hyperphosphorylated C-terminal domain (CTD) (By similarity). Interacts with CDC2L1 or CDC2L2, and SFRS2.,tissue specificity:Ubiquitous with higher level in thymus. Overexpression in primary tumors of head and neck squamous cell carcinomas (HNSCC).,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus speckle . Nucleus, nucleoplasm . Found in nuclear intrachromatin granules clusters (IGC), also called nuclear speckles, which are storage compartments for nuclear proteins involved in mRNA processing. .
组织表达： Widely expressed. Overexpression in primary tumors of head and neck squamous cell carcinomas (HNSCC).
科研货号： PLA015497

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