其他名称: GJA3; Gap junction alpha-3 protein; Connexin-46; Cx46
分子量: 47kD
功能: disease:Defects in GJA3 are the cause of zonular pulverulent cataract type 3 (CZP3) [MIM:601885]. CZP3 is a form of autosomal dominant congenital cataract.,function:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.,similarity:Belongs to the connexin family. Alpha-type (group II) subfamily.,subunit:A connexon is composed of a hexamer of connexins. This particular connexin is a component of lens fiber gap junctions, can form both junctional and non-junctional ("hemi-") channels.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cell membrane ; Multi-pass membrane protein . Cell junction, gap junction .
其他名称: GJA3; Gap junction alpha-3 protein; Connexin-46; Cx46
分子量: 47kD
功能: disease:Defects in GJA3 are the cause of zonular pulverulent cataract type 3 (CZP3) [MIM:601885]. CZP3 is a form of autosomal dominant congenital cataract.,function:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.,similarity:Belongs to the connexin family. Alpha-type (group II) subfamily.,subunit:A connexon is composed of a hexamer of connexins. This particular connexin is a component of lens fiber gap junctions, can form both junctional and non-junctional ("hemi-") channels.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cell membrane ; Multi-pass membrane protein . Cell junction, gap junction .