Claudin-7 Polyclonal Antibody

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商品货号： PLA015300

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： CLDN7
蛋白名称： Claudin-7
Human_gene_id： 1366
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1366
Human_swiss_prot_no： O95471
Human_swiss_link： http://www.uniprot.org/uniprotkb/O95471/entry
Mouse_gene_id： 53624
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=53624
Mouse_swiss_prot_no： Q9Z261
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9Z261
Rat_gene_id： 65132
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=65132
Rat_swiss_prot_no： Q9Z1L1
Rat_swiss_link： http://www.uniprot.org/uniprot/Q9Z1L1
特异性： Claudin-7 Polyclonal Antibody detects endogenous levels of Claudin-7 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CLDN7; CEPTRL2; CPETRL2; Claudin-7; CLDN-7
实测条带： 22kD
信号通路： Cell adhesion molecules (CAMs);Tight junction;Leukocyte transendothelial migration;
功能： function:Plays a major role in tight junction-specific obliteration of the intercellular space.,induction:By androgens.,similarity:Belongs to the claudin family.,subunit:Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.,tissue specificity:Expressed in kidney, lung and prostate. Isoform 1 seems to be predominant, except in some normal prostate samples, where isoform 2 is the major form. Down-regulated in breast cancers, including ductal carcinoma in situ (DCIS), lobular carcinoma in situ (LCIS) and invasive ductal carcinoma (IDC) (at protein level), as well as in several cancer cell lines. Loss of expression correlates with histological grade, occurring predominantly in high-grade lesions.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane ; Multi-pass membrane protein . Basolateral cell membrane . Cell junction, tight junction . Co-localizes with EPCAM at the basolateral cell membrane and tight junction. .
组织表达： Expressed in kidney, lung and prostate. Isoform 1 seems to be predominant, except in some normal prostate samples, where isoform 2 is the major form. Down-regulated in breast cancers, including ductal carcinoma in situ (DCIS), lobular carcinoma in situ (LCIS) and invasive ductal carcinoma (IDC) (at protein level), as well as in several cancer cell lines. Loss of expression correlates with histological grade, occurring predominantly in high-grade lesions.
科研货号： PLA015300

Claudin-7 Polyclonal Antibody

Catalog No PLA015300

Product information

基因名称： CLDN7
蛋白名称： Claudin-7
Human_gene_id： 1366
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1366
Human_swiss_prot_no： O95471
Human_swiss_link： http://www.uniprot.org/uniprotkb/O95471/entry
Mouse_gene_id： 53624
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=53624
Mouse_swiss_prot_no： Q9Z261
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9Z261
Rat_gene_id： 65132
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=65132
Rat_swiss_prot_no： Q9Z1L1
Rat_swiss_link： http://www.uniprot.org/uniprot/Q9Z1L1
特异性： Claudin-7 Polyclonal Antibody detects endogenous levels of Claudin-7 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CLDN7; CEPTRL2; CPETRL2; Claudin-7; CLDN-7
实测条带： 22kD
信号通路： Cell adhesion molecules (CAMs);Tight junction;Leukocyte transendothelial migration;
功能： function:Plays a major role in tight junction-specific obliteration of the intercellular space.,induction:By androgens.,similarity:Belongs to the claudin family.,subunit:Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.,tissue specificity:Expressed in kidney, lung and prostate. Isoform 1 seems to be predominant, except in some normal prostate samples, where isoform 2 is the major form. Down-regulated in breast cancers, including ductal carcinoma in situ (DCIS), lobular carcinoma in situ (LCIS) and invasive ductal carcinoma (IDC) (at protein level), as well as in several cancer cell lines. Loss of expression correlates with histological grade, occurring predominantly in high-grade lesions.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane ; Multi-pass membrane protein . Basolateral cell membrane . Cell junction, tight junction . Co-localizes with EPCAM at the basolateral cell membrane and tight junction. .
组织表达： Expressed in kidney, lung and prostate. Isoform 1 seems to be predominant, except in some normal prostate samples, where isoform 2 is the major form. Down-regulated in breast cancers, including ductal carcinoma in situ (DCIS), lobular carcinoma in situ (LCIS) and invasive ductal carcinoma (IDC) (at protein level), as well as in several cancer cell lines. Loss of expression correlates with histological grade, occurring predominantly in high-grade lesions.
科研货号： PLA015300

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