Claudin-1 Polyclonal Antibody

> > > >

商品货号： PLA015288

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

在线咨询

MSDS

说明书

商品描述

基因名称： CLDN1
蛋白名称： Claudin-1
Human_gene_id： 9076
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9076
Human_swiss_prot_no： O95832
Human_swiss_link： http://www.uniprot.org/uniprotkb/O95832/entry
Mouse_gene_id： 12737
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12737
Mouse_swiss_prot_no： O88551
Mouse_swiss_link： http://www.uniprot.org/uniprot/O88551
Rat_gene_id： 65129
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=65129
Rat_swiss_prot_no： P56745
Rat_swiss_link： http://www.uniprot.org/uniprot/P56745
特异性： Claudin-1 Polyclonal Antibody detects endogenous levels of Claudin-1 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CLDN1; CLD1; SEMP1; Claudin-1; Senescence-associated epithelial membrane protein
实测条带： 22kD
信号通路： Cell adhesion molecules (CAMs);Tight junction;Leukocyte transendothelial migration;Pathogenic Escherichia coli infection;
功能： disease:Defects in CLDN1 are the cause of ichthyosis-sclerosing cholangitis neonatal syndrome (NISCH) [MIM:607626]; also called ichthyosis with leukocyte vacuoles alopecia and sclerosing cholangitis (ILVASC). NISCH is a rare autosomal recessive complex ichthyosis syndrome characterized by scalp hypotrichosis, scarring alopecia, vulgar type ichthyosis, and sclerosing cholangitis.,function:Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity (By similarity). Acts as a co-receptor for HCV entry into hepatic cells.,similarity:Belongs to the claudin family.,subunit:Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN3, but not CLDN2, homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3. Interacts with MPDZ and INADL (By similarity). May interact with HCV E1 and E2 proteins.,tissue specificity:Strongly expressed in liver and kidney. Expressed in heart, brain, spleen, lung and testis.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein . Basolateral cell membrane . Associates with CD81 and the CLDN1-CD81 complex localizes to the basolateral cell membrane. .
组织表达： Strongly expressed in liver and kidney. Expressed in heart, brain, spleen, lung and testis.
tag： hot
科研货号： PLA015288

Claudin-1 Polyclonal Antibody

Catalog No PLA015288

Product information

基因名称： CLDN1
蛋白名称： Claudin-1
Human_gene_id： 9076
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9076
Human_swiss_prot_no： O95832
Human_swiss_link： http://www.uniprot.org/uniprotkb/O95832/entry
Mouse_gene_id： 12737
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12737
Mouse_swiss_prot_no： O88551
Mouse_swiss_link： http://www.uniprot.org/uniprot/O88551
Rat_gene_id： 65129
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=65129
Rat_swiss_prot_no： P56745
Rat_swiss_link： http://www.uniprot.org/uniprot/P56745
特异性： Claudin-1 Polyclonal Antibody detects endogenous levels of Claudin-1 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CLDN1; CLD1; SEMP1; Claudin-1; Senescence-associated epithelial membrane protein
实测条带： 22kD
信号通路： Cell adhesion molecules (CAMs);Tight junction;Leukocyte transendothelial migration;Pathogenic Escherichia coli infection;
功能： disease:Defects in CLDN1 are the cause of ichthyosis-sclerosing cholangitis neonatal syndrome (NISCH) [MIM:607626]; also called ichthyosis with leukocyte vacuoles alopecia and sclerosing cholangitis (ILVASC). NISCH is a rare autosomal recessive complex ichthyosis syndrome characterized by scalp hypotrichosis, scarring alopecia, vulgar type ichthyosis, and sclerosing cholangitis.,function:Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity (By similarity). Acts as a co-receptor for HCV entry into hepatic cells.,similarity:Belongs to the claudin family.,subunit:Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN3, but not CLDN2, homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3. Interacts with MPDZ and INADL (By similarity). May interact with HCV E1 and E2 proteins.,tissue specificity:Strongly expressed in liver and kidney. Expressed in heart, brain, spleen, lung and testis.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein . Basolateral cell membrane . Associates with CD81 and the CLDN1-CD81 complex localizes to the basolateral cell membrane. .
组织表达： Strongly expressed in liver and kidney. Expressed in heart, brain, spleen, lung and testis.
tag： hot
科研货号： PLA015288

Hunan UPT Biotechnology Co.,Ltd

Website：www.uptbio.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.