Cdc14a phosphatase Polyclonal Antibody

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商品货号： PLA015163

适应性： 人,大鼠,小鼠,

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： CDC14A
蛋白名称： Dual specificity protein phosphatase CDC14A
Human_gene_id： 8556
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8556
Human_swiss_prot_no： Q9UNH5
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9UNH5/entry
Mouse_swiss_prot_no： Q6GQT0
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q6GQT0
特异性： Cdc14a phosphatase Polyclonal Antibody detects endogenous levels of Cdc14a phosphatase protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CDC14A; Dual specificity protein phosphatase CDC14A; CDC14 cell division cycle 14 homolog A
实测条带： 66kD
信号通路： Cell_Cycle_G1S;Cell_Cycle_G2M_DNA;
功能： catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,domain:Composed of two structurally equivalent A and B domains that adopt a dual specificity protein phosphatase (DSP) fold.,function:Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.,subcellular location:Centrosomal during interphase, released into the cytoplasm at the onset of mitosis. Subsequently localizes to the midzone of the mitotic spindle.,subunit:Interacts with KIF20A, which is required to localize CDC14 to the midzone of the mitotic spindle.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle pole . Cytoplasm, cytoskeleton, spindle . Cell projection, kinocilium . Cell projection, stereocilium . Centrosomal during interphase, released into the cytoplasm at the onset of mitosis. Subsequently localizes to the mitotic spindle pole and at the central spindle (PubMed:12134069, PubMed:11901424, PubMed:15263015). Present along both the transient kinocilia of developing cochlear hair cells and the persistent kinocilia of vestibular hair cells (By similarity). .
组织表达： Aorta endothelial cell,Brain,Placenta,
科研货号： PLA015163

Cdc14a phosphatase Polyclonal Antibody

Catalog No PLA015163

Product information

基因名称： CDC14A
蛋白名称： Dual specificity protein phosphatase CDC14A
Human_gene_id： 8556
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8556
Human_swiss_prot_no： Q9UNH5
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9UNH5/entry
Mouse_swiss_prot_no： Q6GQT0
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q6GQT0
特异性： Cdc14a phosphatase Polyclonal Antibody detects endogenous levels of Cdc14a phosphatase protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CDC14A; Dual specificity protein phosphatase CDC14A; CDC14 cell division cycle 14 homolog A
实测条带： 66kD
信号通路： Cell_Cycle_G1S;Cell_Cycle_G2M_DNA;
功能： catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,domain:Composed of two structurally equivalent A and B domains that adopt a dual specificity protein phosphatase (DSP) fold.,function:Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.,subcellular location:Centrosomal during interphase, released into the cytoplasm at the onset of mitosis. Subsequently localizes to the midzone of the mitotic spindle.,subunit:Interacts with KIF20A, which is required to localize CDC14 to the midzone of the mitotic spindle.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle pole . Cytoplasm, cytoskeleton, spindle . Cell projection, kinocilium . Cell projection, stereocilium . Centrosomal during interphase, released into the cytoplasm at the onset of mitosis. Subsequently localizes to the mitotic spindle pole and at the central spindle (PubMed:12134069, PubMed:11901424, PubMed:15263015). Present along both the transient kinocilia of developing cochlear hair cells and the persistent kinocilia of vestibular hair cells (By similarity). .
组织表达： Aorta endothelial cell,Brain,Placenta,
科研货号： PLA015163

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