其他名称: CD164; Sialomucin core protein 24; MUC-24; Endolyn; Multi-glycosylated core protein 24; MGC-24; MGC-24v; CD antigen CD164
分子量: 20kD
信号通路: Lysosome;
功能: function:This is a carcinoma-associated protein, probably a mucin.,PTM:Highly N- and O-glycosylated; contains sialic acid.,PTM:The motif Ser-Gly may serve as the site of attachment of a glycosaminoglycan side chain.,similarity:Belongs to the CD164 family.,tissue specificity:Small intestine, colon, lung, thyroid and in colorectal and pancreatic adenocarcinoma.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Lysosome membrane ; Single-pass type I membrane protein . Endosome membrane ; Single-pass type I membrane protein . Cell membrane ; Single-pass type I membrane protein .; [Isoform 2]: Secreted .
组织表达: Isoform 1 and isoform 3 are expressed in hematopoietic and non-hematopoietic tissues. Isoform 1 is expressed by prostate cancer tumors and prostate cancer cell lines. The expression is greater in bone metastases than in primary tumors. Expression in osseous metastasis is greater than that in soft tissue metastasis. Isoform 2 is expressed in the small intestine, colon, lung, thyroid and in colorectal and pancreatic adenocarcinoma. Isoform 4 is expressed by both hematopoietic progenitor cells and bone marrow stromal cells.
其他名称: CD164; Sialomucin core protein 24; MUC-24; Endolyn; Multi-glycosylated core protein 24; MGC-24; MGC-24v; CD antigen CD164
分子量: 20kD
信号通路: Lysosome;
功能: function:This is a carcinoma-associated protein, probably a mucin.,PTM:Highly N- and O-glycosylated; contains sialic acid.,PTM:The motif Ser-Gly may serve as the site of attachment of a glycosaminoglycan side chain.,similarity:Belongs to the CD164 family.,tissue specificity:Small intestine, colon, lung, thyroid and in colorectal and pancreatic adenocarcinoma.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Lysosome membrane ; Single-pass type I membrane protein . Endosome membrane ; Single-pass type I membrane protein . Cell membrane ; Single-pass type I membrane protein .; [Isoform 2]: Secreted .
组织表达: Isoform 1 and isoform 3 are expressed in hematopoietic and non-hematopoietic tissues. Isoform 1 is expressed by prostate cancer tumors and prostate cancer cell lines. The expression is greater in bone metastases than in primary tumors. Expression in osseous metastasis is greater than that in soft tissue metastasis. Isoform 2 is expressed in the small intestine, colon, lung, thyroid and in colorectal and pancreatic adenocarcinoma. Isoform 4 is expressed by both hematopoietic progenitor cells and bone marrow stromal cells.