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Casein Kinase Iε Polyclonal Antibody
商品货号: PLA015059
适 应 性: 人,小鼠
WB IHC IF ELISA
¥600元
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MSDS
说明书
商品描述
  • 基因名称: CSNK1E
  • 蛋白名称: Casein kinase I isoform epsilon
  • Human_gene_id: 1454
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1454
  • Human_swiss_prot_no: P49674
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P49674/entry
  • Mouse_gene_id: 27373
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=27373
  • Mouse_swiss_prot_no: Q9JMK2
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q9JMK2
  • 特异性: Casein Kinase Iε Polyclonal Antibody detects endogenous levels of Casein Kinase Iε protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: CSNK1E; Casein kinase I isoform epsilon; CKI-epsilon; CKIe
  • 实测条带: 47kD
  • 信号通路: WNT;WNT-T CELLHedgehog;Circadian rhythm;
  • 功能: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. May act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. Retains PER1 in the cytoplasm. Inhibits cytokine-induced granuloytic differentiation.,induction:Down-regulated during granulocytic differentiation.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer. Component of the circadian core oscillator, which includes the CRY proteins, CLOCK, or NPAS2, BMAL1 or BMAL2, CSNK1D and/or CSNK1E, TIMELESS and the PER proteins. Interacts directly with PER1 and PER2 which may lead to their degradation. Interacts with ANKRD6 and SOCS3.,tissue specificity:Expressed in all tissues examined, including brain, heart, lung, liver, pancreas, kidney, placenta and skeletal muscle. Expressed in monocytes and lymphocytes but not in granulocytes.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm . Nucleus .
  • 组织表达: Expressed in all tissues examined, including brain, heart, lung, liver, pancreas, kidney, placenta and skeletal muscle. Expressed in monocytes and lymphocytes but not in granulocytes.
  • 科研货号: PLA015059
Casein Kinase Iε Polyclonal Antibody
Catalog No PLA015059
Product information
  • 基因名称: CSNK1E
  • 蛋白名称: Casein kinase I isoform epsilon
  • Human_gene_id: 1454
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1454
  • Human_swiss_prot_no: P49674
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P49674/entry
  • Mouse_gene_id: 27373
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=27373
  • Mouse_swiss_prot_no: Q9JMK2
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q9JMK2
  • 特异性: Casein Kinase Iε Polyclonal Antibody detects endogenous levels of Casein Kinase Iε protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: CSNK1E; Casein kinase I isoform epsilon; CKI-epsilon; CKIe
  • 实测条带: 47kD
  • 信号通路: WNT;WNT-T CELLHedgehog;Circadian rhythm;
  • 功能: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. May act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. Retains PER1 in the cytoplasm. Inhibits cytokine-induced granuloytic differentiation.,induction:Down-regulated during granulocytic differentiation.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer. Component of the circadian core oscillator, which includes the CRY proteins, CLOCK, or NPAS2, BMAL1 or BMAL2, CSNK1D and/or CSNK1E, TIMELESS and the PER proteins. Interacts directly with PER1 and PER2 which may lead to their degradation. Interacts with ANKRD6 and SOCS3.,tissue specificity:Expressed in all tissues examined, including brain, heart, lung, liver, pancreas, kidney, placenta and skeletal muscle. Expressed in monocytes and lymphocytes but not in granulocytes.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm . Nucleus .
  • 组织表达: Expressed in all tissues examined, including brain, heart, lung, liver, pancreas, kidney, placenta and skeletal muscle. Expressed in monocytes and lymphocytes but not in granulocytes.
  • 科研货号: PLA015059
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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