CAF-1 p60 Polyclonal Antibody

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商品货号： PLA015016

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： CHAF1B
蛋白名称： Chromatin assembly factor 1 subunit B
Human_gene_id： 8208
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8208
Human_swiss_prot_no： Q13112
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q13112/entry
Mouse_gene_id： 110749
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=110749
Mouse_swiss_prot_no： Q9D0N7
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9D0N7
特异性： CAF-1 p60 Polyclonal Antibody detects endogenous levels of CAF-1 p60 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CHAF1B; CAF1A; CAF1P60; MPHOSPH7; MPP7; Chromatin assembly factor 1 subunit B; CAF-1 subunit B; Chromatin assembly factor I p60 subunit; CAF-I 60 kDa subunit; CAF-I p60; M-phase phosphoprotein 7
实测条带： 61kD
信号通路： NF_kappaB
功能： developmental stage:Active complex is found in G1, S and G2 phases.,function:Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. The CCR4-NOT complex functions as general transcription regulation complex.,PTM:Differentially phosphorylated during cell cycle. During mitosis the p60 subunit of inactive CAF-1 is hyperphosphorylated and displaced into the cytosol. Progressivly dephosphorylated from G1 to S and G2 phase. Phosphorylated p60 is recruited to chromatin undergoing DNA repair after UV irradiation in G1, S or G2 phases.,similarity:Belongs to the WD repeat HIR1 family.,similarity:Contains 7 WD repeats.,subcellular location:DNA replication foci. Cytoplasmic in M phase.,subunit:Subunit of the CAF-1 complex that contains RBBP4, CHAF1B and CHAF1A. CHAF1A binds directly to CHAF1B. Only minor amounts of RBBP4 are complexed with CHAF1A and CHAF1B in G1 phase. In G2 and S phase also monomeric CHAF1B is detected. Subunit of the CCR4-NOT core complex that contains CHAF1A, CHAF1B, CNOT1, CNOT2, CNOT3, CNOT4, CNOT6 and CNOT8.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm . DNA replication foci. Cytoplasmic in M phase.
组织表达： Epithelium,Lymphoblast,Uterus,
科研货号： PLA015016

CAF-1 p60 Polyclonal Antibody

Catalog No PLA015016

Product information

基因名称： CHAF1B
蛋白名称： Chromatin assembly factor 1 subunit B
Human_gene_id： 8208
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8208
Human_swiss_prot_no： Q13112
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q13112/entry
Mouse_gene_id： 110749
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=110749
Mouse_swiss_prot_no： Q9D0N7
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9D0N7
特异性： CAF-1 p60 Polyclonal Antibody detects endogenous levels of CAF-1 p60 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CHAF1B; CAF1A; CAF1P60; MPHOSPH7; MPP7; Chromatin assembly factor 1 subunit B; CAF-1 subunit B; Chromatin assembly factor I p60 subunit; CAF-I 60 kDa subunit; CAF-I p60; M-phase phosphoprotein 7
实测条带： 61kD
信号通路： NF_kappaB
功能： developmental stage:Active complex is found in G1, S and G2 phases.,function:Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. The CCR4-NOT complex functions as general transcription regulation complex.,PTM:Differentially phosphorylated during cell cycle. During mitosis the p60 subunit of inactive CAF-1 is hyperphosphorylated and displaced into the cytosol. Progressivly dephosphorylated from G1 to S and G2 phase. Phosphorylated p60 is recruited to chromatin undergoing DNA repair after UV irradiation in G1, S or G2 phases.,similarity:Belongs to the WD repeat HIR1 family.,similarity:Contains 7 WD repeats.,subcellular location:DNA replication foci. Cytoplasmic in M phase.,subunit:Subunit of the CAF-1 complex that contains RBBP4, CHAF1B and CHAF1A. CHAF1A binds directly to CHAF1B. Only minor amounts of RBBP4 are complexed with CHAF1A and CHAF1B in G1 phase. In G2 and S phase also monomeric CHAF1B is detected. Subunit of the CCR4-NOT core complex that contains CHAF1A, CHAF1B, CNOT1, CNOT2, CNOT3, CNOT4, CNOT6 and CNOT8.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm . DNA replication foci. Cytoplasmic in M phase.
组织表达： Epithelium,Lymphoblast,Uterus,
科研货号： PLA015016

Hunan UPT Biotechnology Co.,Ltd

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