其他名称： BCAR3; NSP2; SH2D3B; Breast cancer anti-estrogen resistance protein 3; Novel SH2-containing protein 2; SH2 domain-containing protein 3B
实测条带： 92kD
功能： function:May act as an adapter protein and couple activated growth factor receptors to a signaling pathway that regulates the proliferation in breast cancer cells. When overexpressed, it confers anti-estrogen resistance in breast cancer cell lines. May also be regulated by cellular adhesion to extracellular matrix proteins.,PTM:Phosphorylated on tyrosine.,similarity:Contains 1 Ras-GEF domain.,similarity:Contains 1 SH2 domain.,subunit:Interacts with BCAR1, NEDD9, PTK2 and PTPN1.,tissue specificity:Ubiquitously expressed. Found in several cancer cell lines, but not in nonmalignant breast tissue.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Cell junction, focal adhesion . Localization to focal adhesions depends on interaction with PTPRA. .
组织表达： Ubiquitously expressed. Found in several cancer cell lines, but not in nonmalignant breast tissue.
科研货号： PLA014894
BCAR3 Polyclonal Antibody
Catalog NoPLA014894
Product information
基因名称： BCAR3
蛋白名称： Breast cancer anti-estrogen resistance protein 3
其他名称： BCAR3; NSP2; SH2D3B; Breast cancer anti-estrogen resistance protein 3; Novel SH2-containing protein 2; SH2 domain-containing protein 3B
实测条带： 92kD
功能： function:May act as an adapter protein and couple activated growth factor receptors to a signaling pathway that regulates the proliferation in breast cancer cells. When overexpressed, it confers anti-estrogen resistance in breast cancer cell lines. May also be regulated by cellular adhesion to extracellular matrix proteins.,PTM:Phosphorylated on tyrosine.,similarity:Contains 1 Ras-GEF domain.,similarity:Contains 1 SH2 domain.,subunit:Interacts with BCAR1, NEDD9, PTK2 and PTPN1.,tissue specificity:Ubiquitously expressed. Found in several cancer cell lines, but not in nonmalignant breast tissue.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Cell junction, focal adhesion . Localization to focal adhesions depends on interaction with PTPRA. .
组织表达： Ubiquitously expressed. Found in several cancer cell lines, but not in nonmalignant breast tissue.
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