其他名称： ZFHX3; ATBF1; Zinc finger homeobox protein 3; AT motif-binding factor; AT-binding transcription factor 1; Alpha-fetoprotein enhancer-binding protein; Zinc finger homeodomain protein 3; ZFH-3
分子量： 404kD
功能： function:Transcriptional activator that binds to the AT-rich core sequence of the enhancer element of the AFP gene.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 22 C2H2-type zinc fingers.,similarity:Contains 4 homeobox DNA-binding domains.,subunit:Interacts with FNBP3.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm . Translocates from the cytoplasm to the nucleus following TGF-beta stimulation. Expressed in nuclear body (NB)-like dots in the nucleus some of which overlap or closely associate with PML body. .
组织表达： Not found in normal gastric mucosa but found in gastric carcinoma cells (at protein level). Expression is higher in ER-positive breast tumors than ER-negative breast tumors (at protein level).
其他名称： ZFHX3; ATBF1; Zinc finger homeobox protein 3; AT motif-binding factor; AT-binding transcription factor 1; Alpha-fetoprotein enhancer-binding protein; Zinc finger homeodomain protein 3; ZFH-3
分子量： 404kD
功能： function:Transcriptional activator that binds to the AT-rich core sequence of the enhancer element of the AFP gene.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 22 C2H2-type zinc fingers.,similarity:Contains 4 homeobox DNA-binding domains.,subunit:Interacts with FNBP3.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm . Translocates from the cytoplasm to the nucleus following TGF-beta stimulation. Expressed in nuclear body (NB)-like dots in the nucleus some of which overlap or closely associate with PML body. .
组织表达： Not found in normal gastric mucosa but found in gastric carcinoma cells (at protein level). Expression is higher in ER-positive breast tumors than ER-negative breast tumors (at protein level).
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