Asf1a Polyclonal Antibody

> > > >

商品货号： PLA014810

适应性： 人,小鼠

￥600元

规格：

40μL 100μL 200μL

在线咨询

MSDS

说明书

商品描述

基因名称： ASF1A
蛋白名称： Histone chaperone ASF1A
Human_gene_id： 25842
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25842
Human_swiss_prot_no： Q9Y294
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9Y294/entry
Mouse_gene_id： 66403
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=66403
Mouse_swiss_prot_no： Q9CQE6
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9CQE6
特异性： Asf1a Polyclonal Antibody detects endogenous levels of Asf1a protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： ASF1A; CGI-98; HSPC146; Histone chaperone ASF1A; Anti-silencing function protein 1 homolog A; hAsf1; hAsf1a; CCG1-interacting factor A; CIA; hCIA
实测条带： 23kD
功能： function:Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.,PTM:Phosphorylated by TLK1 and TLK2. Highly phosphorylated in S-phase and at lower levels in M-phase.,similarity:Belongs to the ASF1 family.,subunit:Interacts with histone H3 (including both histone H3.1 and H3.3) and histone H4. Interacts with the CHAF1A, CHAF1B and RBBP4 subunits of the CAF-1 complex. Interacts with CABIN1, HAT1, HIRA, NASP, TAF1, TLK1, TLK2 and UBN1.,tissue specificity:Ubiquitously expressed.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus .
组织表达： Ubiquitously expressed.
科研货号： PLA014810

Asf1a Polyclonal Antibody

Catalog No PLA014810

Product information

基因名称： ASF1A
蛋白名称： Histone chaperone ASF1A
Human_gene_id： 25842
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25842
Human_swiss_prot_no： Q9Y294
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9Y294/entry
Mouse_gene_id： 66403
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=66403
Mouse_swiss_prot_no： Q9CQE6
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9CQE6
特异性： Asf1a Polyclonal Antibody detects endogenous levels of Asf1a protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： ASF1A; CGI-98; HSPC146; Histone chaperone ASF1A; Anti-silencing function protein 1 homolog A; hAsf1; hAsf1a; CCG1-interacting factor A; CIA; hCIA
实测条带： 23kD
功能： function:Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.,PTM:Phosphorylated by TLK1 and TLK2. Highly phosphorylated in S-phase and at lower levels in M-phase.,similarity:Belongs to the ASF1 family.,subunit:Interacts with histone H3 (including both histone H3.1 and H3.3) and histone H4. Interacts with the CHAF1A, CHAF1B and RBBP4 subunits of the CAF-1 complex. Interacts with CABIN1, HAT1, HIRA, NASP, TAF1, TLK1, TLK2 and UBN1.,tissue specificity:Ubiquitously expressed.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus .
组织表达： Ubiquitously expressed.
科研货号： PLA014810

Hunan UPT Biotechnology Co.,Ltd

Website：www.uptbio.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.