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Arginase I Polyclonal Antibody
商品货号: PLA014757
适 应 性: 人,小鼠,大鼠
WB IHC IF ELISA
¥600元
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MSDS
说明书
商品描述
  • 基因名称: ARG1
  • 蛋白名称: Arginase-1
  • Human_gene_id: 383
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=383
  • Human_swiss_prot_no: P05089
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P05089/entry
  • Mouse_swiss_prot_no: Q61176
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q61176
  • 特异性: Arginase I Polyclonal Antibody detects endogenous levels of Arginase I protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: IHC-p: 100-300.WB 1:500 - 1:2000. ELISA: 1:5000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: ARG1; Arginase-1; Liver-type arginase; Type I arginase
  • 实测条带: 35kD
  • 信号通路: Arginine and proline metabolism;
  • 功能: catalytic activity:L-arginine + H(2)O = L-ornithine + urea.,cofactor:Binds 2 manganese ions per subunit.,disease:Defects in ARG1 are the cause of argininemia (ARGIN) [MIM:207800]; also known as hyperargininemia. Argininemia is a rare autosomal recessive disorder of the urea cycle. Arginine is elevated in the blood and cerebrospinal fluid, and periodic hyperammonemia occurs. Clinical manifestations include developmental delay, seizures, mental retardation, hypotonia, ataxia, progressive spastic quadriplegia.,induction:By arginine or homoarginine.,online information:Arginase entry,pathway:Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1.,similarity:Belongs to the arginase family.,subunit:Homotrimer.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm . Cytoplasmic granule . Localized in azurophil granules of neutrophils (PubMed:15546957). .
  • 组织表达: Within the immune system initially reported to be selectively expressed in granulocytes (polymorphonuclear leukocytes [PMNs]) (PubMed:15546957). Also detected in macrophages mycobacterial granulomas (PubMed:23749634). Expressed in group2 innate lymphoid cells (ILC2s) during lung disease (PubMed:27043409).
  • 科研货号: PLA014757
Arginase I Polyclonal Antibody
Catalog No PLA014757
Product information
  • 基因名称: ARG1
  • 蛋白名称: Arginase-1
  • Human_gene_id: 383
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=383
  • Human_swiss_prot_no: P05089
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P05089/entry
  • Mouse_swiss_prot_no: Q61176
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q61176
  • 特异性: Arginase I Polyclonal Antibody detects endogenous levels of Arginase I protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: IHC-p: 100-300.WB 1:500 - 1:2000. ELISA: 1:5000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: ARG1; Arginase-1; Liver-type arginase; Type I arginase
  • 实测条带: 35kD
  • 信号通路: Arginine and proline metabolism;
  • 功能: catalytic activity:L-arginine + H(2)O = L-ornithine + urea.,cofactor:Binds 2 manganese ions per subunit.,disease:Defects in ARG1 are the cause of argininemia (ARGIN) [MIM:207800]; also known as hyperargininemia. Argininemia is a rare autosomal recessive disorder of the urea cycle. Arginine is elevated in the blood and cerebrospinal fluid, and periodic hyperammonemia occurs. Clinical manifestations include developmental delay, seizures, mental retardation, hypotonia, ataxia, progressive spastic quadriplegia.,induction:By arginine or homoarginine.,online information:Arginase entry,pathway:Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1.,similarity:Belongs to the arginase family.,subunit:Homotrimer.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm . Cytoplasmic granule . Localized in azurophil granules of neutrophils (PubMed:15546957). .
  • 组织表达: Within the immune system initially reported to be selectively expressed in granulocytes (polymorphonuclear leukocytes [PMNs]) (PubMed:15546957). Also detected in macrophages mycobacterial granulomas (PubMed:23749634). Expressed in group2 innate lymphoid cells (ILC2s) during lung disease (PubMed:27043409).
  • 科研货号: PLA014757
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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