其他名称： ARFGAP3; ARFGAP1; ADP-ribosylation factor GTPase-activating protein 3; ARF GAP 3
实测条带： 60kD
信号通路： Endocytosis;
功能： caution:Was originally (PubMed:10704287) termed ARFGAP1.,developmental stage:Expressed at higher level in adult thymus, brain and lung, than in corresponding fetal tissues. Expressed at lower level in spleen, heart, kidney and liver during development.,enzyme regulation:GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2).,function:GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.,similarity:Contains 1 Arf-GAP domain.,subcellular location:Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment.,tissue specificity:Widely expressed. Highest expression in endocrine glands (pancreas, pituary gland, salivary gland, and prostate) and testis with a much higher expression in the testis than in the ovary.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Golgi apparatus membrane ; Peripheral membrane protein ; Cytoplasmic side . Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment.
组织表达： Widely expressed. Highest expression in endocrine glands (pancreas, pituitary gland, salivary gland, and prostate) and testis with a much higher expression in the testis than in the ovary.
科研货号： PLA014753
ARF GAP3 Polyclonal Antibody
Catalog NoPLA014753
Product information
基因名称： ARFGAP3
蛋白名称： ADP-ribosylation factor GTPase-activating protein 3
其他名称： ARFGAP3; ARFGAP1; ADP-ribosylation factor GTPase-activating protein 3; ARF GAP 3
实测条带： 60kD
信号通路： Endocytosis;
功能： caution:Was originally (PubMed:10704287) termed ARFGAP1.,developmental stage:Expressed at higher level in adult thymus, brain and lung, than in corresponding fetal tissues. Expressed at lower level in spleen, heart, kidney and liver during development.,enzyme regulation:GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2).,function:GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.,similarity:Contains 1 Arf-GAP domain.,subcellular location:Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment.,tissue specificity:Widely expressed. Highest expression in endocrine glands (pancreas, pituary gland, salivary gland, and prostate) and testis with a much higher expression in the testis than in the ovary.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Golgi apparatus membrane ; Peripheral membrane protein ; Cytoplasmic side . Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment.
组织表达： Widely expressed. Highest expression in endocrine glands (pancreas, pituitary gland, salivary gland, and prostate) and testis with a much higher expression in the testis than in the ovary.
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