ARF GAP1 Polyclonal Antibody

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商品货号： PLA014752

适应性： 人,小鼠,大鼠,猴,牛

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： ARFGAP1
蛋白名称： ADP-ribosylation factor GTPase-activating protein 1
Human_gene_id： 55738
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55738
Human_swiss_prot_no： Q8N6T3
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q8N6T3/entry
Mouse_gene_id： 228998
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=228998
Mouse_swiss_prot_no： Q9EPJ9
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9EPJ9
Rat_gene_id： 246310
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=246310
Rat_swiss_prot_no： Q62848
Rat_swiss_link： http://www.uniprot.org/uniprot/Q62848
特异性： ARF GAP1 Polyclonal Antibody detects endogenous levels of ARF GAP1 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： ARFGAP1; ARF1GAP; ADP-ribosylation factor GTPase-activating protein 1; ARF GAP 1; ADP-ribosylation factor 1 GTPase-activating protein; ARF1 GAP; ARF1-directed GTPase-activating protein
实测条带： 48kD
信号通路： Endocytosis;
功能： domain:The region downstream of Arf-GAP domain is essential to GAP activity in vivo. This region may be required for its targeting to Golgi membranes.,function:GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and RNP24. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine.,sequence caution:Intron retention.,similarity:Contains 1 Arf-GAP domain.,subcellular location:Associates with the Golgi complex.,subunit:Interacts with ARF1. Interacts with the COPI coat proteins, KDELR1 and RNP24. The interaction with RNP24 inhibits the GAP activity.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Golgi apparatus . Associates with the Golgi complex. .
组织表达： Brain,Epithelium,Fetal brain,Testis,
科研货号： PLA014752

ARF GAP1 Polyclonal Antibody

Catalog No PLA014752

Product information

基因名称： ARFGAP1
蛋白名称： ADP-ribosylation factor GTPase-activating protein 1
Human_gene_id： 55738
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55738
Human_swiss_prot_no： Q8N6T3
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q8N6T3/entry
Mouse_gene_id： 228998
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=228998
Mouse_swiss_prot_no： Q9EPJ9
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9EPJ9
Rat_gene_id： 246310
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=246310
Rat_swiss_prot_no： Q62848
Rat_swiss_link： http://www.uniprot.org/uniprot/Q62848
特异性： ARF GAP1 Polyclonal Antibody detects endogenous levels of ARF GAP1 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： ARFGAP1; ARF1GAP; ADP-ribosylation factor GTPase-activating protein 1; ARF GAP 1; ADP-ribosylation factor 1 GTPase-activating protein; ARF1 GAP; ARF1-directed GTPase-activating protein
实测条带： 48kD
信号通路： Endocytosis;
功能： domain:The region downstream of Arf-GAP domain is essential to GAP activity in vivo. This region may be required for its targeting to Golgi membranes.,function:GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and RNP24. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine.,sequence caution:Intron retention.,similarity:Contains 1 Arf-GAP domain.,subcellular location:Associates with the Golgi complex.,subunit:Interacts with ARF1. Interacts with the COPI coat proteins, KDELR1 and RNP24. The interaction with RNP24 inhibits the GAP activity.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Golgi apparatus . Associates with the Golgi complex. .
组织表达： Brain,Epithelium,Fetal brain,Testis,
科研货号： PLA014752

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