其他名称: ANXA2; ANX2; ANX2L4; CAL1H; LPC2D; Annexin A2; Annexin II; Annexin-2; Calpactin I heavy chain; Calpactin-1 heavy chain; Chromobindin-8; Lipocortin II; Placental anticoagulant protein IV; PAP-IV; Protein I; p36
实测条带: 38kD
功能: domain:A pair of annexin repeats may form one binding site for calcium and phospholipid.,function:Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response.,miscellaneous:It may cross-link plasma membrane phospholipids with actin and the cytoskeleton and be involved with exocytosis.,online information:Red velvet - Issue 86 of September 2007,PTM:Phosphorylation of Tyr-24 enhances heat stress-induced translocation to the cell surface.,similarity:Belongs to the annexin family.,similarity:Contains 4 annexin repeats.,subcellular location:In the lamina beneath the plasma membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Translocated from the cytoplasm to the cell surface through a Golgi-independent mechanism.,subunit:Heterotetramer containing 2 light chains of S100A10/p11 and 2 heavy chains of ANXA2/p36. Interacts with ATP1B1 and DYSF.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Secreted, extracellular space, extracellular matrix, basement membrane . Melanosome . In the lamina beneath the plasma membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Translocated from the cytoplasm to the cell surface through a Golgi-independent mechanism.
其他名称: ANXA2; ANX2; ANX2L4; CAL1H; LPC2D; Annexin A2; Annexin II; Annexin-2; Calpactin I heavy chain; Calpactin-1 heavy chain; Chromobindin-8; Lipocortin II; Placental anticoagulant protein IV; PAP-IV; Protein I; p36
实测条带: 38kD
功能: domain:A pair of annexin repeats may form one binding site for calcium and phospholipid.,function:Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response.,miscellaneous:It may cross-link plasma membrane phospholipids with actin and the cytoskeleton and be involved with exocytosis.,online information:Red velvet - Issue 86 of September 2007,PTM:Phosphorylation of Tyr-24 enhances heat stress-induced translocation to the cell surface.,similarity:Belongs to the annexin family.,similarity:Contains 4 annexin repeats.,subcellular location:In the lamina beneath the plasma membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Translocated from the cytoplasm to the cell surface through a Golgi-independent mechanism.,subunit:Heterotetramer containing 2 light chains of S100A10/p11 and 2 heavy chains of ANXA2/p36. Interacts with ATP1B1 and DYSF.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Secreted, extracellular space, extracellular matrix, basement membrane . Melanosome . In the lamina beneath the plasma membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Translocated from the cytoplasm to the cell surface through a Golgi-independent mechanism.