其他名称： AKAP8; AKAP95; A-kinase anchor protein 8; AKAP-8; A-kinase anchor protein 95 kDa; AKAP 95
实测条带： 76kD
功能： function:Anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase (PKA type II).,similarity:Belongs to the AKAP95 family.,subcellular location:Associated with the nuclear matrix. Redistributed and detached from condensed chromatin during mitosis.,subunit:Binds to dimeric RII-alpha regulatory subunit of PKA during mitosis.,tissue specificity:Highly expressed in heart, liver, skeletal muscle, kidney and pancreas.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Nucleus matrix . Nucleus, nucleolus . Cytoplasm . Associated with the nuclear matrix in interphase and redistributes mostly to chromatin at mitosis. However, mitotic chromatin localization has been questioned. Upon nuclear reassembly at the end of mitosis, is sequestered into the daughter nuclei where it re-acquires an interphase distribution. Exhibits partial localization to the nucleolus in interphase, where it colocalizes with UBTF/UBF, suggesting localization to the fibrillary center and/or to the dense fibrillary component. Colocalizes with GJA1 at the nuclear membrane specifically during cell cycle G1/S phase. .
组织表达： Highly expressed in heart, liver, skeletal muscle, kidney and pancreas. Expressed in mature dendritic cells.
其他名称： AKAP8; AKAP95; A-kinase anchor protein 8; AKAP-8; A-kinase anchor protein 95 kDa; AKAP 95
实测条带： 76kD
功能： function:Anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase (PKA type II).,similarity:Belongs to the AKAP95 family.,subcellular location:Associated with the nuclear matrix. Redistributed and detached from condensed chromatin during mitosis.,subunit:Binds to dimeric RII-alpha regulatory subunit of PKA during mitosis.,tissue specificity:Highly expressed in heart, liver, skeletal muscle, kidney and pancreas.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Nucleus matrix . Nucleus, nucleolus . Cytoplasm . Associated with the nuclear matrix in interphase and redistributes mostly to chromatin at mitosis. However, mitotic chromatin localization has been questioned. Upon nuclear reassembly at the end of mitosis, is sequestered into the daughter nuclei where it re-acquires an interphase distribution. Exhibits partial localization to the nucleolus in interphase, where it colocalizes with UBTF/UBF, suggesting localization to the fibrillary center and/or to the dense fibrillary component. Colocalizes with GJA1 at the nuclear membrane specifically during cell cycle G1/S phase. .
组织表达： Highly expressed in heart, liver, skeletal muscle, kidney and pancreas. Expressed in mature dendritic cells.
在线咨询
湘公网安备