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AKAP 10 Polyclonal Antibody
商品货号: PLA014636
适 应 性: 人,小鼠,大鼠
WB IHC IF ELISA
¥600元
规格:
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MSDS
说明书
商品描述
  • 基因名称: AKAP10
  • 蛋白名称: A-kinase anchor protein 10 mitochondrial
  • Human_gene_id: 11216
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11216
  • Human_swiss_prot_no: O43572
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/O43572/entry
  • Mouse_gene_id: 56697
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56697
  • Mouse_swiss_prot_no: O88845
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/O88845
  • 特异性: AKAP 10 Polyclonal Antibody detects endogenous levels of AKAP 10 protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: AKAP10; A-kinase anchor protein 10; mitochondrial; AKAP-10; Dual specificity A kinase-anchoring protein 2; D-AKAP-2; Protein kinase A-anchoring protein 10; PRKA10
  • 实测条带: 73kD
  • 功能: domain:RII-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.,function:Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase.,similarity:Contains 2 RGS domains.,subcellular location:Predominantly mitochondrial but also membrane associated and cytoplasmic.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Mitochondrion . Membrane . Cytoplasm . Predominantly mitochondrial but also membrane associated and cytoplasmic.
  • 组织表达: Brain,Lung,
  • 科研货号: PLA014636
AKAP 10 Polyclonal Antibody
Catalog No PLA014636
Product information
  • 基因名称: AKAP10
  • 蛋白名称: A-kinase anchor protein 10 mitochondrial
  • Human_gene_id: 11216
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11216
  • Human_swiss_prot_no: O43572
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/O43572/entry
  • Mouse_gene_id: 56697
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56697
  • Mouse_swiss_prot_no: O88845
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/O88845
  • 特异性: AKAP 10 Polyclonal Antibody detects endogenous levels of AKAP 10 protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: AKAP10; A-kinase anchor protein 10; mitochondrial; AKAP-10; Dual specificity A kinase-anchoring protein 2; D-AKAP-2; Protein kinase A-anchoring protein 10; PRKA10
  • 实测条带: 73kD
  • 功能: domain:RII-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.,function:Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase.,similarity:Contains 2 RGS domains.,subcellular location:Predominantly mitochondrial but also membrane associated and cytoplasmic.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Mitochondrion . Membrane . Cytoplasm . Predominantly mitochondrial but also membrane associated and cytoplasmic.
  • 组织表达: Brain,Lung,
  • 科研货号: PLA014636
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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