其他名称： ACOT8; ACTEIII; PTE1; PTE2; Acyl-coenzyme A thioesterase 8; Acyl-CoA thioesterase 8; Choloyl-coenzyme A thioesterase; HIV-Nef-associated acyl-CoA thioesterase; PTE-2; Peroxisomal acyl-coenzyme A thioester hydrolase 1; PTE-1; Peroxisomal lon
实测条带： 36kD
功能： catalytic activity:Choloyl-CoA + H(2)O = cholate + CoA.,function:Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May mediate Nef-induced down-regulation of CD4. Major thioesterase in peroxisomes. Competes with BAAT (Bile acid CoA: amino acid N-acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). Shows a preference for medium-length fatty acyl-CoAs (By similarity). May be involved in the metabolic regulation of peroxisome proliferation.,induction:Regulated by peroxisome proliferator (such as Clofibrate), via the peroxisome proliferator-activated receptors (PPARs).,similarity:Belongs to the C/M/P thioester hydrolase family.,subunit:Interacts with HIV-1 Nef.,tissue specificity:Detected in a T-cell line (at protein level). Ubiquitous.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Peroxisome matrix . Predominantly localized in the peroxisome but a localization to the cytosol cannot be excluded. .
组织表达： Detected in a T-cell line (at protein level). Ubiquitous (PubMed:9153233, PubMed:9299485).
其他名称： ACOT8; ACTEIII; PTE1; PTE2; Acyl-coenzyme A thioesterase 8; Acyl-CoA thioesterase 8; Choloyl-coenzyme A thioesterase; HIV-Nef-associated acyl-CoA thioesterase; PTE-2; Peroxisomal acyl-coenzyme A thioester hydrolase 1; PTE-1; Peroxisomal lon
实测条带： 36kD
功能： catalytic activity:Choloyl-CoA + H(2)O = cholate + CoA.,function:Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May mediate Nef-induced down-regulation of CD4. Major thioesterase in peroxisomes. Competes with BAAT (Bile acid CoA: amino acid N-acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). Shows a preference for medium-length fatty acyl-CoAs (By similarity). May be involved in the metabolic regulation of peroxisome proliferation.,induction:Regulated by peroxisome proliferator (such as Clofibrate), via the peroxisome proliferator-activated receptors (PPARs).,similarity:Belongs to the C/M/P thioester hydrolase family.,subunit:Interacts with HIV-1 Nef.,tissue specificity:Detected in a T-cell line (at protein level). Ubiquitous.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Peroxisome matrix . Predominantly localized in the peroxisome but a localization to the cytosol cannot be excluded. .
组织表达： Detected in a T-cell line (at protein level). Ubiquitous (PubMed:9153233, PubMed:9299485).
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