功能: catalytic activity:CoA-[4'-phosphopantetheine] + apo-[acyl-carrier-protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier-protein].,cofactor:Binds 1 magnesium ion.,function:Catalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4'-phosphopantetheine moiety from coenzyme A to a serine residue of a broad range of acceptors, such as the acyl carrier domain of FASN.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the P-Pant transferase superfamily. AcpS family.,subunit:Monomer. Interacts with FASN.,tissue specificity:Detected in heart, skeletal muscle, placenta, testis, brain, pancreas, liver and kidney.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cytoplasm, cytosol .
组织表达: Detected in heart, skeletal muscle, placenta, testis, brain, pancreas, liver and kidney.
功能: catalytic activity:CoA-[4'-phosphopantetheine] + apo-[acyl-carrier-protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier-protein].,cofactor:Binds 1 magnesium ion.,function:Catalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4'-phosphopantetheine moiety from coenzyme A to a serine residue of a broad range of acceptors, such as the acyl carrier domain of FASN.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the P-Pant transferase superfamily. AcpS family.,subunit:Monomer. Interacts with FASN.,tissue specificity:Detected in heart, skeletal muscle, placenta, testis, brain, pancreas, liver and kidney.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cytoplasm, cytosol .
组织表达: Detected in heart, skeletal muscle, placenta, testis, brain, pancreas, liver and kidney.