其他名称： UBQLN4; C1orf6; CIP75; UBIN; Ubiquilin-4; Ataxin-1 interacting ubiquitin-like protein; A1Up; Ataxin-1 ubiquitin-like-interacting protein A1U; Connexin43-interacting protein of 75 kDa; CIP75
实测条带： 54kD
功能： PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 UBA domain.,similarity:Contains 1 ubiquitin-like domain.,subcellular location:May associate with the endoplasmic reticulum.,subunit:Homodimer. Binds SCA1. Binds signal sequences of proteins that are targeted to the endoplasmic reticulum.,tissue specificity:Highly expressed in pancreas, kidney, skeletal muscle, heart and throughout the brain, and at lower levels in placenta, lung and liver.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm . Chromosome . Endoplasmic reticulum . Cytoplasm, perinuclear region . Cytoplasmic vesicle, autophagosome . Colocalizes with the proteasome, both in nucleus and cytoplasm (PubMed:15280365). Exported from the nucleus following interaction with DESI1/POST (PubMed:29666234). In response to DNA damage and phosphorylation at Ser-318 by ATM, localizes to the nucleus and is recruited to sites of DNA damage (PubMed:30612738). .
组织表达： Highly expressed in pancreas, kidney, skeletal muscle, heart and throughout the brain, and at lower levels in placenta, lung and liver.
其他名称： UBQLN4; C1orf6; CIP75; UBIN; Ubiquilin-4; Ataxin-1 interacting ubiquitin-like protein; A1Up; Ataxin-1 ubiquitin-like-interacting protein A1U; Connexin43-interacting protein of 75 kDa; CIP75
实测条带： 54kD
功能： PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 UBA domain.,similarity:Contains 1 ubiquitin-like domain.,subcellular location:May associate with the endoplasmic reticulum.,subunit:Homodimer. Binds SCA1. Binds signal sequences of proteins that are targeted to the endoplasmic reticulum.,tissue specificity:Highly expressed in pancreas, kidney, skeletal muscle, heart and throughout the brain, and at lower levels in placenta, lung and liver.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm . Chromosome . Endoplasmic reticulum . Cytoplasm, perinuclear region . Cytoplasmic vesicle, autophagosome . Colocalizes with the proteasome, both in nucleus and cytoplasm (PubMed:15280365). Exported from the nucleus following interaction with DESI1/POST (PubMed:29666234). In response to DNA damage and phosphorylation at Ser-318 by ATM, localizes to the nucleus and is recruited to sites of DNA damage (PubMed:30612738). .
组织表达： Highly expressed in pancreas, kidney, skeletal muscle, heart and throughout the brain, and at lower levels in placenta, lung and liver.
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