A Cyclase VIII Polyclonal Antibody

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商品货号： PLA014516

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： ADCY8
蛋白名称： Adenylate cyclase type 8
Human_gene_id： 114
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=114
Human_swiss_prot_no： P40145
Human_swiss_link： http://www.uniprot.org/uniprotkb/P40145/entry
Mouse_gene_id： 11514
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11514
Mouse_swiss_prot_no： P97490
Mouse_swiss_link： http://www.uniprot.org/uniprot/P97490
Rat_gene_id： 29241
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29241
Rat_swiss_prot_no： P40146
Rat_swiss_link： http://www.uniprot.org/uniprot/P40146
特异性： A Cyclase VIII Polyclonal Antibody detects endogenous levels of A Cyclase VIII protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： ADCY8; Adenylate cyclase type 8; ATP pyrophosphate-lyase 8; Adenylate cyclase type VIII; Adenylyl cyclase 8; AC8; Ca(2+)/calmodulin-activated adenylyl cyclase
分子量： 140kD
信号通路： Purine metabolism;Calcium;Chemokine;Oocyte meiosis;Vascular smooth muscle contraction;Gap junction;Long-term potentiation;Taste transduction;GnRH;Progesterone-mediated oocyte maturation;Melanogenesis;Dilated cardiomyopathy;
功能： catalytic activity:ATP = 3',5'-cyclic AMP + diphosphate.,cofactor:Binds 2 magnesium ions per subunit.,enzyme regulation:Activated by calcium/calmodulin.,function:This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence.,similarity:Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.,similarity:Contains 2 guanylate cyclase domains.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane ; Multi-pass membrane protein . Basolateral cell membrane . Apical cell membrane . Cell junction, synapse . Cell projection, dendrite . Cell projection, axon . Cell junction, synapse, presynaptic cell membrane . Cell junction, synapse, postsynaptic density . Membrane raft . Membrane, coated pit . Cytoplasmic vesicle, clathrin-coated vesicle membrane . Membrane, caveola . Localized to dendritic arbors (By similarity). Monomeric N-glycosylated species localizes in membrane raft. In contrast, monomeric unglycosylated forms are enriched in clathrin-coated pits and vesicles. Dimers are also localized outside of membrane rafts. Membrane raft localization and integrity is indispensable for CCE-stimulated adenylate cyclase activity (By similarity). .
组织表达： Detected in brain cortex (PubMed:1715695). Expressed in islet (PubMed:25403481).
科研货号： PLA014516

A Cyclase VIII Polyclonal Antibody

Catalog No PLA014516

Product information

基因名称： ADCY8
蛋白名称： Adenylate cyclase type 8
Human_gene_id： 114
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=114
Human_swiss_prot_no： P40145
Human_swiss_link： http://www.uniprot.org/uniprotkb/P40145/entry
Mouse_gene_id： 11514
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11514
Mouse_swiss_prot_no： P97490
Mouse_swiss_link： http://www.uniprot.org/uniprot/P97490
Rat_gene_id： 29241
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29241
Rat_swiss_prot_no： P40146
Rat_swiss_link： http://www.uniprot.org/uniprot/P40146
特异性： A Cyclase VIII Polyclonal Antibody detects endogenous levels of A Cyclase VIII protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： ADCY8; Adenylate cyclase type 8; ATP pyrophosphate-lyase 8; Adenylate cyclase type VIII; Adenylyl cyclase 8; AC8; Ca(2+)/calmodulin-activated adenylyl cyclase
分子量： 140kD
信号通路： Purine metabolism;Calcium;Chemokine;Oocyte meiosis;Vascular smooth muscle contraction;Gap junction;Long-term potentiation;Taste transduction;GnRH;Progesterone-mediated oocyte maturation;Melanogenesis;Dilated cardiomyopathy;
功能： catalytic activity:ATP = 3',5'-cyclic AMP + diphosphate.,cofactor:Binds 2 magnesium ions per subunit.,enzyme regulation:Activated by calcium/calmodulin.,function:This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence.,similarity:Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.,similarity:Contains 2 guanylate cyclase domains.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane ; Multi-pass membrane protein . Basolateral cell membrane . Apical cell membrane . Cell junction, synapse . Cell projection, dendrite . Cell projection, axon . Cell junction, synapse, presynaptic cell membrane . Cell junction, synapse, postsynaptic density . Membrane raft . Membrane, coated pit . Cytoplasmic vesicle, clathrin-coated vesicle membrane . Membrane, caveola . Localized to dendritic arbors (By similarity). Monomeric N-glycosylated species localizes in membrane raft. In contrast, monomeric unglycosylated forms are enriched in clathrin-coated pits and vesicles. Dimers are also localized outside of membrane rafts. Membrane raft localization and integrity is indispensable for CCE-stimulated adenylate cyclase activity (By similarity). .
组织表达： Detected in brain cortex (PubMed:1715695). Expressed in islet (PubMed:25403481).
科研货号： PLA014516

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