14-3-3 σ Polyclonal Antibody

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商品货号： PLA014496

适应性： 人,小鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： SFN
蛋白名称： 14-3-3 protein sigma
Human_gene_id： 2810
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2810
Human_swiss_prot_no： P31947
Human_swiss_link： http://www.uniprot.org/uniprotkb/P31947/entry
Mouse_gene_id： 55948
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55948
Mouse_swiss_prot_no： O70456
Mouse_swiss_link： http://www.uniprot.org/uniprot/O70456
特异性： 14-3-3 σ Polyclonal Antibody detects endogenous levels of 14-3-3 σ protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： IHC-p: 100-300.WB 1:500 - 1:2000. ELISA: 1:20000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： SFN; HME1; 14-3-3 protein sigma; Epithelial cell marker protein 1; Stratifin
实测条带： 30kD
信号通路： Cell_Cycle_G1S;Cell_Cycle_G2M_DNA;p53;Aldosterone-regulated sodium reabsorption;
功能： function:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.,function:p53-regulated inhibitor of G2/M progression.,similarity:Belongs to the 14-3-3 family.,subcellular location:May be secreted by a non-classical secretory pathway.,subunit:Homodimer. Interacts with KRT17 (By similarity). Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN.,tissue specificity:Present mainly in tissues enriched in stratified squamous keratinising epithelium.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm. Nucleus . Secreted. May be secreted by a non-classical secretory pathway.
组织表达： Present mainly in tissues enriched in stratified squamous keratinizing epithelium.
科研货号： PLA014496

14-3-3 σ Polyclonal Antibody

Catalog No PLA014496

Product information

基因名称： SFN
蛋白名称： 14-3-3 protein sigma
Human_gene_id： 2810
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2810
Human_swiss_prot_no： P31947
Human_swiss_link： http://www.uniprot.org/uniprotkb/P31947/entry
Mouse_gene_id： 55948
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55948
Mouse_swiss_prot_no： O70456
Mouse_swiss_link： http://www.uniprot.org/uniprot/O70456
特异性： 14-3-3 σ Polyclonal Antibody detects endogenous levels of 14-3-3 σ protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： IHC-p: 100-300.WB 1:500 - 1:2000. ELISA: 1:20000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： SFN; HME1; 14-3-3 protein sigma; Epithelial cell marker protein 1; Stratifin
实测条带： 30kD
信号通路： Cell_Cycle_G1S;Cell_Cycle_G2M_DNA;p53;Aldosterone-regulated sodium reabsorption;
功能： function:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.,function:p53-regulated inhibitor of G2/M progression.,similarity:Belongs to the 14-3-3 family.,subcellular location:May be secreted by a non-classical secretory pathway.,subunit:Homodimer. Interacts with KRT17 (By similarity). Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN.,tissue specificity:Present mainly in tissues enriched in stratified squamous keratinising epithelium.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm. Nucleus . Secreted. May be secreted by a non-classical secretory pathway.
组织表达： Present mainly in tissues enriched in stratified squamous keratinizing epithelium.
科研货号： PLA014496

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