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PHEX rabbit pAb
商品货号: PLA014387
适 应 性: 人,小鼠
WB
¥600元
规格:
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MSDS
说明书
商品描述
  • 基因名称: PHEX PEX
  • 蛋白名称: Phosphate-regulating neutral endopeptidase (EC 3.4.24.-) (Metalloendopeptidase homolog PEX) (Vitamin D-resistant hypophosphatemic rickets protein) (X-linked hypophosphatemia protein) (HYP)
  • Human_gene_id: 5251
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5251
  • Human_swiss_prot_no: P78562
  • Human_swiss_link: https://www.uniprot.org/uniprot/P78562
  • Mouse_gene_id: 18675
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18675
  • Mouse_swiss_prot_no: P70669
  • Mouse_swiss_link: https://www.uniprot.org/uniprotkb/P70669/entry
  • 特异性: This antibody detects endogenous levels of PHEX at Human, Mouse
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 分子量: 82kD
  • 功能: Peptidase that cleaves SIBLING (small integrin-binding ligand, N-linked glycoprotein)-derived ASARM peptides, thus regulating their biological activity . Cleaves ASARM peptides between Ser and Glu or Asp residues . Regulates osteogenic cell differentiation and bone mineralization through the cleavage of the MEPE-derived ASARM peptide . Promotes dentin mineralization and renal phosphate reabsorption by cleaving DMP1- and MEPE-derived ASARM peptides . Inhibits the cleavage of MEPE by CTSB/cathepsin B thus preventing MEPE degradation .
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cell membrane ; Single-pass type II membrane protein .
  • 组织表达: Specifically expressed in ovary (PubMed:9070861). Expressed at low levels in kidney (PubMed:9070861).
  • 科研货号: PLA014387
PHEX rabbit pAb
Catalog No PLA014387
Product information
  • 基因名称: PHEX PEX
  • 蛋白名称: Phosphate-regulating neutral endopeptidase (EC 3.4.24.-) (Metalloendopeptidase homolog PEX) (Vitamin D-resistant hypophosphatemic rickets protein) (X-linked hypophosphatemia protein) (HYP)
  • Human_gene_id: 5251
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5251
  • Human_swiss_prot_no: P78562
  • Human_swiss_link: https://www.uniprot.org/uniprot/P78562
  • Mouse_gene_id: 18675
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18675
  • Mouse_swiss_prot_no: P70669
  • Mouse_swiss_link: https://www.uniprot.org/uniprotkb/P70669/entry
  • 特异性: This antibody detects endogenous levels of PHEX at Human, Mouse
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 分子量: 82kD
  • 功能: Peptidase that cleaves SIBLING (small integrin-binding ligand, N-linked glycoprotein)-derived ASARM peptides, thus regulating their biological activity . Cleaves ASARM peptides between Ser and Glu or Asp residues . Regulates osteogenic cell differentiation and bone mineralization through the cleavage of the MEPE-derived ASARM peptide . Promotes dentin mineralization and renal phosphate reabsorption by cleaving DMP1- and MEPE-derived ASARM peptides . Inhibits the cleavage of MEPE by CTSB/cathepsin B thus preventing MEPE degradation .
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cell membrane ; Single-pass type II membrane protein .
  • 组织表达: Specifically expressed in ovary (PubMed:9070861). Expressed at low levels in kidney (PubMed:9070861).
  • 科研货号: PLA014387
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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