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ANO6 rabbit pAb
商品货号: PLA014346
适 应 性: 人,小鼠
WB
¥600元
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MSDS
说明书
商品描述
  • 基因名称: ANO6 TMEM16F
  • 蛋白名称: Anoctamin-6 (Transmembrane protein 16F)
  • Human_gene_id: 196527
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=196527
  • Human_swiss_prot_no: Q4KMQ2
  • Human_swiss_link: https://www.uniprot.org/uniprot/Q4KMQ2
  • Mouse_gene_id: 105722
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=105722
  • Mouse_swiss_prot_no: Q6P9J9
  • Mouse_swiss_link: https://www.uniprot.org/uniprotkb/Q6P9J9/entry
  • 特异性: This antibody detects endogenous levels of ANO6 at Human, Mouse
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 分子量: 100kD
  • 功能: Small-conductance calcium-activated nonselective cation (SCAN) channel which acts as a regulator of phospholipid scrambling in platelets and osteoblasts. Phospholipid scrambling results in surface exposure of phosphatidylserine which in platelets is essential to trigger the clotting system whereas in osteoblasts is essential for the deposition of hydroxyapatite during bone mineralization. Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Can generate outwardly rectifying chloride channel currents in airway epithelial cells and Jurkat T lymphocytes. ; Upon SARS coronavirus-2/SARS-CoV-2 infection, is activated by spike protein which increases the amplitude of spontaneous Ca(2+) signals and is required for spike-mediated syncytia.
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cell membrane ; Multi-pass membrane protein . Shows an intracellular localization according to PubMed:22075693.
  • 组织表达: Expressed in embryonic stem cell, fetal liver, retina, chronic myologenous leukemia and intestinal cancer.
  • 科研货号: PLA014346
ANO6 rabbit pAb
Catalog No PLA014346
Product information
  • 基因名称: ANO6 TMEM16F
  • 蛋白名称: Anoctamin-6 (Transmembrane protein 16F)
  • Human_gene_id: 196527
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=196527
  • Human_swiss_prot_no: Q4KMQ2
  • Human_swiss_link: https://www.uniprot.org/uniprot/Q4KMQ2
  • Mouse_gene_id: 105722
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=105722
  • Mouse_swiss_prot_no: Q6P9J9
  • Mouse_swiss_link: https://www.uniprot.org/uniprotkb/Q6P9J9/entry
  • 特异性: This antibody detects endogenous levels of ANO6 at Human, Mouse
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 分子量: 100kD
  • 功能: Small-conductance calcium-activated nonselective cation (SCAN) channel which acts as a regulator of phospholipid scrambling in platelets and osteoblasts. Phospholipid scrambling results in surface exposure of phosphatidylserine which in platelets is essential to trigger the clotting system whereas in osteoblasts is essential for the deposition of hydroxyapatite during bone mineralization. Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Can generate outwardly rectifying chloride channel currents in airway epithelial cells and Jurkat T lymphocytes. ; Upon SARS coronavirus-2/SARS-CoV-2 infection, is activated by spike protein which increases the amplitude of spontaneous Ca(2+) signals and is required for spike-mediated syncytia.
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cell membrane ; Multi-pass membrane protein . Shows an intracellular localization according to PubMed:22075693.
  • 组织表达: Expressed in embryonic stem cell, fetal liver, retina, chronic myologenous leukemia and intestinal cancer.
  • 科研货号: PLA014346
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    E-mail:service@uptbio.com
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