功能： Involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits.
相关产品： RS0001,RS0002,YM3028,YM3029
组织表达： Expressed at low levels in brain. Expression is highly increased in glioma tissues.
科研货号： PLA014099
EFTUD1 rabbit pAb
Catalog NoPLA014099
Product information
基因名称： EFTUD1 EFL1 FAM42A
蛋白名称： Elongation factor Tu GTP-binding domain-containing protein 1 (Elongation factor-like 1) (Protein FAM42A)
功能： Involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits.
相关产品： RS0001,RS0002,YM3028,YM3029
组织表达： Expressed at low levels in brain. Expression is highly increased in glioma tissues.
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