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PPM1D rabbit pAb
商品货号: PLA014078
适 应 性: 人,小鼠
WB
¥600元
规格:
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MSDS
说明书
商品描述
  • 基因名称: PPM1D WIP1
  • 蛋白名称: Protein phosphatase 1D (EC 3.1.3.16) (Protein phosphatase 2C isoform delta) (PP2C-delta) (Protein phosphatase magnesium-dependent 1 delta) (p53-induced protein phosphatase 1)
  • Human_gene_id: 8493
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8493
  • Human_swiss_prot_no: O15297
  • Human_swiss_link: https://www.uniprot.org/uniprot/O15297
  • Mouse_gene_id: 53892
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=53892
  • Mouse_swiss_prot_no: Q9QZ67
  • Mouse_swiss_link: https://www.uniprot.org/uniprotkb/Q9QZ67/entry
  • 特异性: This antibody detects endogenous levels of PPM1D at Human, Mouse
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 分子量: 67kD
  • 功能: Involved in the negative regulation of p53 expression . Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins . Mediates MAPK14 dephosphorylation and inactivation . Is also an important regulator of global heterochromatin silencing and critical in maintaining genome integrity (By similarity).
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Nucleus . Cytoplasm, cytosol .
  • 组织表达: Expressed in fetal and adult brain. Also detected in fetal liver and skeletal muscle, but not in their adult counterparts.
  • 科研货号: PLA014078
PPM1D rabbit pAb
Catalog No PLA014078
Product information
  • 基因名称: PPM1D WIP1
  • 蛋白名称: Protein phosphatase 1D (EC 3.1.3.16) (Protein phosphatase 2C isoform delta) (PP2C-delta) (Protein phosphatase magnesium-dependent 1 delta) (p53-induced protein phosphatase 1)
  • Human_gene_id: 8493
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8493
  • Human_swiss_prot_no: O15297
  • Human_swiss_link: https://www.uniprot.org/uniprot/O15297
  • Mouse_gene_id: 53892
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=53892
  • Mouse_swiss_prot_no: Q9QZ67
  • Mouse_swiss_link: https://www.uniprot.org/uniprotkb/Q9QZ67/entry
  • 特异性: This antibody detects endogenous levels of PPM1D at Human, Mouse
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 分子量: 67kD
  • 功能: Involved in the negative regulation of p53 expression . Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins . Mediates MAPK14 dephosphorylation and inactivation . Is also an important regulator of global heterochromatin silencing and critical in maintaining genome integrity (By similarity).
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Nucleus . Cytoplasm, cytosol .
  • 组织表达: Expressed in fetal and adult brain. Also detected in fetal liver and skeletal muscle, but not in their adult counterparts.
  • 科研货号: PLA014078
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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