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MAML1 rabbit pAb
商品货号: PLA013995
适 应 性: 人,小鼠
WB
¥600元
规格:
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MSDS
说明书
商品描述
  • 基因名称: MAML1 KIAA0200
  • 蛋白名称: Mastermind-like protein 1 (Mam-1)
  • Human_gene_id: 9794
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9794
  • Human_swiss_prot_no: Q92585
  • Human_swiss_link: https://www.uniprot.org/uniprot/Q92585
  • Mouse_gene_id: 103806
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=103806
  • Mouse_swiss_prot_no: Q6T264
  • Mouse_swiss_link: https://www.uniprot.org/uniprotkb/Q6T264/entry
  • 特异性: This antibody detects endogenous levels of MAML1 at Human, Mouse
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 分子量: 112kD
  • 功能: Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation and localization of CREBBP to nuclear foci. Plays a role in hematopoietic development by regulating NOTCH-mediated lymphoid cell fate decisions.
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Nucleus speckle . Nuclear, in a punctate manner.
  • 组织表达: Widely expressed with highest levels in heart, pancreas, peripheral blood leukocytes and spleen.
  • 科研货号: PLA013995
MAML1 rabbit pAb
Catalog No PLA013995
Product information
  • 基因名称: MAML1 KIAA0200
  • 蛋白名称: Mastermind-like protein 1 (Mam-1)
  • Human_gene_id: 9794
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9794
  • Human_swiss_prot_no: Q92585
  • Human_swiss_link: https://www.uniprot.org/uniprot/Q92585
  • Mouse_gene_id: 103806
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=103806
  • Mouse_swiss_prot_no: Q6T264
  • Mouse_swiss_link: https://www.uniprot.org/uniprotkb/Q6T264/entry
  • 特异性: This antibody detects endogenous levels of MAML1 at Human, Mouse
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 分子量: 112kD
  • 功能: Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation and localization of CREBBP to nuclear foci. Plays a role in hematopoietic development by regulating NOTCH-mediated lymphoid cell fate decisions.
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Nucleus speckle . Nuclear, in a punctate manner.
  • 组织表达: Widely expressed with highest levels in heart, pancreas, peripheral blood leukocytes and spleen.
  • 科研货号: PLA013995
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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