功能： Protease responsible for filaggrin processing, essential for the maintenance of a proper epidermis organization.
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Membrane ; Single-pass membrane protein .
组织表达： Expressed primarily in the granular layer of the epidermis and inner root sheath of hair follicles. In psoriatic skin, expressed throughout the stratum corneum. In ulcerated skin, expressed in the stratum granulosum of intact epidermis but almost absent from ulcerated regions. Expressed in differentiated areas of squamous cell carcinomas but not in undifferentiated tumors.
功能： Protease responsible for filaggrin processing, essential for the maintenance of a proper epidermis organization.
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Membrane ; Single-pass membrane protein .
组织表达： Expressed primarily in the granular layer of the epidermis and inner root sheath of hair follicles. In psoriatic skin, expressed throughout the stratum corneum. In ulcerated skin, expressed in the stratum granulosum of intact epidermis but almost absent from ulcerated regions. Expressed in differentiated areas of squamous cell carcinomas but not in undifferentiated tumors.
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