功能： Involved in mitotic nuclear envelope reassembly by promoting dephosphorylation of BAF/BANF1 during mitotic exit . Coordinates the control of BAF/BANF1 dephosphorylation by inhibiting VRK1 kinase and promoting dephosphorylation of BAF/BANF1 by protein phosphatase 2A (PP2A), thereby facilitating nuclear envelope assembly . May regulate nuclear localization of VRK1 in non-dividing cells . It is unclear whether it acts as a real PP2A regulatory subunit or whether it is involved in recruitment of the PP2A complex . Involved in brain development .
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Endoplasmic reticulum membrane ; Single-pass type III membrane protein .
科研货号： PLA013959
ANKLE2 rabbit pAb
Catalog NoPLA013959
Product information
基因名称： ANKLE2 KIAA0692 LEM4
蛋白名称： Ankyrin repeat and LEM domain-containing protein 2 (LEM domain-containing protein 4)
功能： Involved in mitotic nuclear envelope reassembly by promoting dephosphorylation of BAF/BANF1 during mitotic exit . Coordinates the control of BAF/BANF1 dephosphorylation by inhibiting VRK1 kinase and promoting dephosphorylation of BAF/BANF1 by protein phosphatase 2A (PP2A), thereby facilitating nuclear envelope assembly . May regulate nuclear localization of VRK1 in non-dividing cells . It is unclear whether it acts as a real PP2A regulatory subunit or whether it is involved in recruitment of the PP2A complex . Involved in brain development .
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Endoplasmic reticulum membrane ; Single-pass type III membrane protein .
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